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患有心房颤动的运动员的中风:一项叙述性综述。

Stroke in Athletes with Atrial Fibrillation: A Narrative Review.

作者信息

Certo Pereira Joana, Lima Maria Rita, Moscoso Costa Francisco, Gomes Daniel A, Maltês Sérgio, Cunha Gonçalo, Dores Hélder, Adragão Pedro

机构信息

Hospital de Santa Cruz, 2790-134 Lisbon, Portugal.

Hospital da Luz, 1500-650 Lisbon, Portugal.

出版信息

Diagnostics (Basel). 2024 Dec 25;15(1):9. doi: 10.3390/diagnostics15010009.

DOI:10.3390/diagnostics15010009
PMID:39795537
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11720530/
Abstract

Atrial fibrillation (AF) is the most common sustained arrhythmia, linked with a significantly heightened risk of stroke. While moderate exercise reduces AF risk, high-level endurance athletes paradoxically exhibit a higher incidence. However, their stroke risk remains uncertain due to their younger age, higher cardiovascular fitness, and lower rate of comorbidities. Several key studies highlight that AF may increase the risk of stroke in endurance athletes, particularly those over 65. However, the overall risk within this population remains relatively low. Notably, older male athletes show a higher AF incidence but experience lower stroke risk than their non-athletic counterparts. Regular physical activity prior to a first stroke appears to reduce mortality, though recurrent stroke risk in athletes with AF mirrors that of non-athletes, despite an elevated AF incidence. Management of AF in athletes is complex, with limited evidence guiding anti-thrombotic strategies. In this setting, specific recommendations are sparse, particularly in sports where bleeding risk is heightened. Individualized management, emphasizing shared decision-making, is critical to balance stroke prevention with athletic performance. Rhythm control strategies, such as catheter ablation, may be a reasonable first-line treatment option for athletes, particularly in those desiring to avoid long-term medication. This review synthesizes the current literature on the incidence, predictors, and management of stroke in athletes with AF.

摘要

心房颤动(AF)是最常见的持续性心律失常,与中风风险显著升高有关。适度运动可降低房颤风险,但高水平耐力运动员却反常地呈现出更高的发病率。然而,由于他们年龄较轻、心血管健康状况较好且合并症发生率较低,其中风风险仍不确定。多项关键研究强调,房颤可能会增加耐力运动员尤其是65岁以上运动员的中风风险。不过,这一人群中的总体风险仍然相对较低。值得注意的是,老年男性运动员房颤发病率较高,但与非运动员同龄人相比,中风风险较低。首次中风前的规律体育活动似乎可降低死亡率,尽管房颤运动员的复发性中风风险与非运动员相当,但其房颤发病率较高。运动员房颤的管理很复杂,指导抗血栓形成策略的证据有限。在这种情况下,具体建议很少,尤其是在出血风险增加的运动项目中。强调共同决策的个体化管理对于平衡中风预防和运动表现至关重要。节律控制策略,如导管消融术,可能是运动员合理的一线治疗选择,特别是对于那些希望避免长期用药的运动员。本综述综合了目前关于房颤运动员中风发病率、预测因素和管理的文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cec7/11720530/cc5a83db03ce/diagnostics-15-00009-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cec7/11720530/cc5a83db03ce/diagnostics-15-00009-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cec7/11720530/cc5a83db03ce/diagnostics-15-00009-g001.jpg

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本文引用的文献

1
2024 ESC Guidelines for the management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS).2024年欧洲心脏病学会(ESC)心房颤动管理指南,与欧洲心胸外科学会(EACTS)联合制定。
Eur Heart J. 2024 Sep 29;45(36):3314-3414. doi: 10.1093/eurheartj/ehae176.
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Atrial fibrillation and stroke: State-of-the-art and future directions.
心房颤动与中风:现状与未来方向。
Curr Probl Cardiol. 2024 Jan;49(1 Pt C):102181. doi: 10.1016/j.cpcardiol.2023.102181. Epub 2023 Oct 31.
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Association between catheter ablation of atrial fibrillation and mortality or stroke.房颤导管消融与死亡率或卒中性事件的关联。
Heart. 2024 Jan 10;110(3):163-169. doi: 10.1136/heartjnl-2023-322883.
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Atrial fibrillation in female endurance athletes.女性耐力运动员的心房颤动
Eur J Prev Cardiol. 2024 Mar 27;31(5):e27-e29. doi: 10.1093/eurjpc/zwad218.
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Atrial fibrillation catheter ablation in endurance athletes: systematic review and meta-analysis.耐力运动员的心房颤动导管消融:系统评价和荟萃分析。
J Interv Card Electrophysiol. 2024 Mar;67(2):329-339. doi: 10.1007/s10840-023-01574-0. Epub 2023 Jul 19.
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Elite female endurance athletes are at increased risk of atrial fibrillation compared to the general population: a matched cohort study.与普通人群相比,精英女性耐力运动员发生心房颤动的风险增加:一项匹配队列研究。
Br J Sports Med. 2023 Sep;57(18):1175-1179. doi: 10.1136/bjsports-2022-106035. Epub 2023 Jul 10.
8
Cardiovascular Safety of Testosterone-Replacement Therapy.睾酮替代疗法的心血管安全性。
N Engl J Med. 2023 Jul 13;389(2):107-117. doi: 10.1056/NEJMoa2215025. Epub 2023 Jun 16.
9
Left atrial dyssynchrony in veteran endurance athletes with and without paroxysmal atrial fibrillation.有和无阵发性心房颤动的资深耐力运动员的左房不同步。
Echocardiography. 2023 Jul;40(7):679-686. doi: 10.1111/echo.15634. Epub 2023 Jun 6.
10
The Autonomic Coumel Triangle: A New Way to Define the Fascinating Relationship between Atrial Fibrillation and the Autonomic Nervous System.自主神经库梅尔三角:定义心房颤动与自主神经系统之间迷人关系的新方法。
Life (Basel). 2023 May 8;13(5):1139. doi: 10.3390/life13051139.