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不同脂肪酸组成的食用油对大鼠血脂及肠道菌群的影响

Effect of Dietary Oils with Different Fatty Acid Compositions on Serum Lipid and Gut Microbiota of Rats.

作者信息

Zhu Tingwei, Kuai Yiming, Guo Xingfeng, Bu Guanhao, Yang Chenxian, Chen Fusheng

机构信息

College of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, China.

出版信息

Foods. 2024 Dec 29;14(1):61. doi: 10.3390/foods14010061.

DOI:10.3390/foods14010061
PMID:39796351
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11720656/
Abstract

The effects of three dietary oils (rapeseed oil, camellia oil, linseed oil) with different fatty acid compositions on the growth performance, digestion and gut microbiota of rats after 8 weeks of feeding were studied. The serum metabolic index and liver histomorphology of rats were measured using an automatic biochemical analyzer and light microscope. Furthermore, 16S rDNA amplicon sequencing technology was used to analyze the gut microbiota. It was found that these differences in fatty acid composition had no significant effect on body fat and liver tissue. However, after digestion, the rapeseed oil group showed lowest triglyceride content (1.22 ± 0.15) and a lower LDL/HDL ratio (0.41 ± 0.02). For gut microbiota distribution, the linseed oil group showed a higher / ratio (6.11 ± 0.54) and a high proportion of . These data indicate that both the unsaturated fatty acid content and n-3 unsaturated fatty acids collectively had an effect on digestion metabolism, and the influence order may be n-3 unsaturated fatty acids > unsaturated fatty acid content.

摘要

研究了三种脂肪酸组成不同的膳食油(菜籽油、山茶油、亚麻籽油)对大鼠喂养8周后的生长性能、消化和肠道微生物群的影响。使用自动生化分析仪和光学显微镜测量大鼠的血清代谢指标和肝脏组织形态学。此外,采用16S rDNA扩增子测序技术分析肠道微生物群。结果发现,这些脂肪酸组成的差异对体脂和肝脏组织没有显著影响。然而,消化后,菜籽油组的甘油三酯含量最低(1.22±0.15),低密度脂蛋白/高密度脂蛋白比值较低(0.41±0.02)。对于肠道微生物群分布,亚麻籽油组的/比值较高(6.11±0.54),且的比例较高。这些数据表明,不饱和脂肪酸含量和n-3不饱和脂肪酸共同对消化代谢有影响,影响顺序可能为n-3不饱和脂肪酸>不饱和脂肪酸含量。

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