Hostein J, Bost R, Carpentier P, Franco A, Fournet J
Gastroenterol Clin Biol. 1985 Feb;9(2):130-5.
Fifty-five consecutive subjects with Raynaud's phenomenon were submitted to esophageal manometry. According to the results of clinical examination and periungual capillaroscopy, they were divided into three groups: sixteen patients presented presclerodermal Raynaud's phenomenon, and nineteen, systemic sclerosis; twenty others had Raynaud's disease. Twenty volunteers formed the control group. Esophageal motor disorders were observed in the group with presclerodermal Raynaud's phenomenon, affecting the esophageal lower sphincter and the peristalsis of the body of the esophagus. In the group with systemic sclerosis, these motor disorders were associated with alterations in the amplitude and the duration of contractions. Esophageal motility was normal in subjects with Raynaud's disease. We can conclude that: 1) esophageal motor disorders can be seen in presclerodermal Raynaud's phenomenon. The kind of abnormalities observed at this stage of the disease are in favor of an early alteration of the neurogenic component of esophageal motility; 2) there is no relationship between esophageal motor disorders and Raynaud's phenomenon in scleroderma.
连续55例患有雷诺现象的患者接受了食管测压。根据临床检查和甲周毛细血管镜检查结果，他们被分为三组：16例患者表现为硬皮病前期雷诺现象，19例为系统性硬化症；另外20例患有雷诺病。20名志愿者组成对照组。在硬皮病前期雷诺现象组中观察到食管运动障碍，影响食管下括约肌和食管体部的蠕动。在系统性硬化症组中，这些运动障碍与收缩幅度和持续时间的改变有关。雷诺病患者的食管动力正常。我们可以得出以下结论：1）在硬皮病前期雷诺现象中可出现食管运动障碍。在疾病的这一阶段观察到的异常类型有利于食管动力神经成分的早期改变；2）在硬皮病中，食管运动障碍与雷诺现象之间没有关系。
