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牛津髋关节评分在全髋关节置换术后1年和2年显示出中度天花板效应:哪些患者有风险,这有关系吗?

The Oxford hip score demonstrates moderate ceiling effects at one and two years after total hip arthroplasty: which patients are at risk and does it matter?

作者信息

Clement N D, Jones S, Qaddoura B, Afzal I, Kader D F

机构信息

Southwest of London Orthopaedic Elective Centre, Epsom, UK.

Edinburgh Orthopaedics, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, UK.

出版信息

Eur J Orthop Surg Traumatol. 2025 Jan 11;35(1):54. doi: 10.1007/s00590-024-04155-7.

Abstract

BACKGROUND

The aim was to assess whether the postoperative Oxford Hip Score (OHS) demonstrated a ceiling effect at 1 or 2 years after total hip arthroplasty (THA) and to identify which patients are more likely to achieve a ceiling score and whether this limits assessment of their outcome.

METHODS

A retrospective cohort of 7871 patients undergoing primary THA was identified from an established arthroplasty database. Patient demographics, ASA grade, socioeconomic status, OHS and EuroQol questionnaire were collected preoperatively and at 1 and 2 years postoperatively. Regression analysis was used to identify independent preoperative factors associated with achieving a ceiling score. Receiver operating characteristic curves were used to identify preoperative OHS's that predicted a postoperative ceiling score.

RESULTS

The ceiling effect (proportion achieving the maximal score) at 1 year was 21.8% (n = 1372) which increased significantly (p < 0.001) to 26.6% (n = 1569) at 2 years. Female gender (p ≤ 0.028), younger age (p < 0.001), decreasing socioeconomic deprivation (only for 2-year OHS), a better preoperative OHS (p < 0.001) or EQ-VAS (p < 0.001) were independently associated with a ceiling OHS postoperatively. The preoperative OHS was demonstrated to be a  poor discriminator of achieving postoperative ceiling score at 1 year (AUC 62.4%, 95% CI 60.7 to 64.1, p < 0.001) and 2 years (AUC 61.5%, 95% CI 60.0 to 63.2). Those achieving a postoperative ceiling OHS at 1 and 2 years had statistically significant (p < 0.001) greater improvements in their OHS, EQ-5D and EQ-VAS and were more likely to have achieved a minimal important change in their OHS relative to their preoperative baseline and a postoperative patient acceptable symptom state.

CONCLUSION

The OHS demonstrated moderate ceiling effects at both 1 and 2 years following THA, and the preoperative score was a predictor of achieving a ceiling score. However, it would seem the ceiling effect did not limit the potential for improvements relative to baseline and achieving clinically meaningful values in the OHS.

摘要

背景

目的是评估全髋关节置换术(THA)后1年或2年的牛津髋关节评分(OHS)是否显示出天花板效应,并确定哪些患者更有可能获得天花板分数,以及这是否限制了对其结果的评估。

方法

从一个已建立的关节置换数据库中确定了7871例行初次THA的患者的回顾性队列。术前以及术后1年和2年收集患者的人口统计学资料、美国麻醉医师协会(ASA)分级、社会经济状况、OHS和欧洲五维健康量表问卷。采用回归分析确定与获得天花板分数相关的独立术前因素。使用受试者工作特征曲线来确定预测术后天花板分数的术前OHS。

结果

1年时的天花板效应(达到最高分的比例)为21.8%(n = 1372),2年时显著增加(p < 0.001)至26.6%(n = 1569)。女性(p≤0.028)、年龄较小(p < 0.001)、社会经济剥夺程度降低(仅适用于2年OHS)、术前OHS较好(p < 0.001)或欧洲五维健康量表视觉模拟量表(EQ-VAS)较好(p < 0.001)与术后OHS达到天花板效应独立相关。术前OHS在1年(曲线下面积[AUC] 62.4%,95%可信区间[CI] 60.7至64.1,p < 0.001)和2年(AUC 61.5%,95% CI 60.0至63.2)时对预测术后天花板分数的辨别能力较差。在1年和2年达到术后OHS天花板效应的患者,其OHS、EQ-5D和EQ-VAS有统计学显著改善(p < 0.001),并且相对于术前基线,其OHS更有可能实现最小重要变化以及达到术后患者可接受的症状状态。

结论

THA后1年和2年OHS均显示出中度天花板效应,术前分数是获得天花板分数的一个预测指标。然而,天花板效应似乎并未限制相对于基线的改善潜力以及在OHS中获得临床有意义的值。

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