Li Hangting, Zhao Wei, Chen Lingxi, Ruan Jiayin, Wu Xiaolian
The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian Road, Shangcheng District, Hangzhou, 310000, China.
School of Nursing, Zhejiang Chinese Medical University, 548 Binwen Road, Binjiang District, Hangzhou, 310000, China.
Eur J Oncol Nurs. 2025 Feb;74:102772. doi: 10.1016/j.ejon.2024.102772. Epub 2024 Dec 21.
Unrelated haematopoietic stem cell donors face physical and psychological discomforts, which aggravate their fear and hesitation and reduce their consent rate and donation efficiency. However, the available experience in the management of these symptoms is insufficient, and strong evidence and guidance are lacking. The symptom experiences of Chinese unrelated haematopoietic stem cell donors were explored.
A descriptive qualitative study was conducted, and the COREQ checklist was used. Between July and December 2023, 14 Chinese unrelated haematopoietic stem cell donors were selected through purposive sampling and underwent semi-structured interviews. Conventional content analysis was used for data analysis.
Three themes and 10 sub-themes were identified as follows: 1) feelings towards symptoms (symptoms appear in clusters, symptoms fluctuate over time, and psychological burden outweigh physical burden); 2) attitude towards symptoms (acceptance, ambivalence, and persistence); 3) needs derived from symptoms (information needs, emotional needs, physiological needs, and expectations for the specialised support provider).
This study provide a basis for healthcare providers to conduct targeted and effective symptom interventions. We emphasise not only helping unrelated donors alleviate symptoms, but also improving their ability to cope with and accept symptoms through the provision of information and emotional support, thus reducing the adverse impact of symptoms on their quality of life and the efficiency of haematopoietic stem cell collection.
非血缘造血干细胞捐献者面临身体和心理上的不适，这加剧了他们的恐惧和犹豫，降低了他们的同意率和捐献效率。然而，目前在这些症状管理方面的经验不足，缺乏有力的证据和指导。本研究旨在探索中国非血缘造血干细胞捐献者的症状体验。
采用描述性定性研究方法，并使用COREQ清单。2023年7月至12月期间，通过目的抽样选取了14名中国非血缘造血干细胞捐献者，进行半结构化访谈。采用常规内容分析法进行数据分析。
确定了三个主题和10个子主题，具体如下：1）对症状的感受（症状呈簇出现、症状随时间波动、心理负担超过身体负担）；2）对症状的态度（接受、矛盾和坚持）；3）症状衍生的需求（信息需求、情感需求、生理需求以及对专业支持提供者的期望）。
本研究为医护人员进行有针对性的有效症状干预提供了依据。我们强调不仅要帮助非血缘捐献者缓解症状，还要通过提供信息和情感支持提高他们应对和接受症状的能力，从而减少症状对其生活质量和造血干细胞采集效率的不利影响。
