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食用罂粟籽后尿液中的吗啡水平。

Morphine levels in urine subsequent to poppy seed consumption.

作者信息

Fritschi G, Prescott W R

出版信息

Forensic Sci Int. 1985 Feb;27(2):111-7. doi: 10.1016/0379-0738(85)90173-2.

DOI:10.1016/0379-0738(85)90173-2
PMID:3979930
Abstract

Urine morphine levels after the consumption of poppy seeds were measured in two separate trials. Maximum levels of approximately 18 micrograms/ml were found using RIA, EMIT-ST and GC methodologies. Positive immunoassay results were seen up to 60 h post-ingestion. Several different lots of seeds from various sources were assayed for morphine and found to range from 4-200 mg/kg. Differentiation of poppy seed eaters from opiate users was not possible via the identification of minor alkaloid constituents of poppy seeds. It is, however, possible to analyse opiate urines with respect to 6-O-acetylmorphine. Below the level of approximately 5 micrograms/ml total opiates, GC/MS is the method of choice for this analysis.

摘要

在两项独立试验中测量了食用罂粟籽后的尿吗啡水平。使用放射免疫分析(RIA)、酶放大免疫分析技术(EMIT-ST)和气相色谱(GC)方法发现最大水平约为18微克/毫升。摄入后60小时内免疫分析结果呈阳性。对来自不同来源的几个不同批次的种子进行吗啡检测,发现含量范围为4 - 200毫克/千克。通过鉴定罂粟籽中的次要生物碱成分,无法区分食用罂粟籽者和阿片类药物使用者。然而,针对6 - O - 乙酰吗啡分析阿片类尿液是可行的。当总阿片类物质水平低于约5微克/毫升时,气相色谱/质谱联用(GC/MS)是此分析的首选方法。

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引用本文的文献

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Concentrations of Morphine and Codeine in Paired Oral Fluid and Urine Specimens Following Ingestion of a Poppy Seed Roll and Raw Poppy Seeds.摄入罂粟籽面包卷和生罂粟籽后配对口腔液和尿液样本中吗啡和可待因的浓度。
J Anal Toxicol. 2015 Oct;39(8):655-61. doi: 10.1093/jat/bkv081.
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Morphine and codeine in oral fluid after controlled poppy seed administration.服用被控制的罂粟籽后口腔液中的吗啡和可待因。
Drug Test Anal. 2015 Jul;7(7):586-91. doi: 10.1002/dta.1742. Epub 2014 Oct 24.
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Morphine and codeine concentrations in human urine following controlled poppy seeds administration of known opiate content.
在已知鸦片含量的罂粟籽受控给药后人体尿液中的吗啡和可待因浓度。
Forensic Sci Int. 2014 Aug;241:87-90. doi: 10.1016/j.forsciint.2014.04.042. Epub 2014 May 14.
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Fatal intoxications in Denmark following intake of morphine from opium poppies.丹麦因摄入罂粟中的吗啡导致的致命中毒事件。
Z Rechtsmed. 1988;101(3):197-204.