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Predictive nomogram integrating radiomics and multi-omics for improved prognosis-model in cholangiocarcinoma.

作者信息

Jia Yunlu, Wan Mingyu, Shen Yifei, Wang Junli, Luo Xiao, He Mengye, Bai Ruiliang, Xiao Wenbo, Zhang Xiaochen, Ruan Jian

机构信息

Department of Medical Oncology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Department of Laboratory Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

出版信息

Clin Transl Med. 2025 Jan;15(1):e70171. doi: 10.1002/ctm2.70171.

DOI:10.1002/ctm2.70171
PMID:39799416
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11726632/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/11726632/4a742797c27f/CTM2-15-e70171-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/11726632/bb79d08dd0b2/CTM2-15-e70171-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/11726632/7c2deb843c7e/CTM2-15-e70171-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/11726632/15998eefa7b2/CTM2-15-e70171-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/11726632/4a742797c27f/CTM2-15-e70171-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/11726632/bb79d08dd0b2/CTM2-15-e70171-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/11726632/7c2deb843c7e/CTM2-15-e70171-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/11726632/15998eefa7b2/CTM2-15-e70171-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/11726632/4a742797c27f/CTM2-15-e70171-g002.jpg

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本文引用的文献

1
The Biological Meaning of Radiomic Features.放射组特征的生物学意义。
Radiology. 2021 Mar;298(3):505-516. doi: 10.1148/radiol.2021202553. Epub 2021 Jan 5.
2
Tumor Mutational Burden as a Predictive Biomarker in Solid Tumors.肿瘤突变负荷作为实体瘤的预测性生物标志物。
Cancer Discov. 2020 Dec;10(12):1808-1825. doi: 10.1158/2159-8290.CD-20-0522. Epub 2020 Nov 2.
3
Distinct clinical and prognostic implication of IDH1/2 mutation and other most frequent mutations in large duct and small duct subtypes of intrahepatic cholangiocarcinoma.
IDH1/2 突变和其他常见突变在大导管型和小导管型肝内胆管细胞癌中的不同临床和预后意义。
BMC Cancer. 2020 Apr 15;20(1):318. doi: 10.1186/s12885-020-06804-6.
4
A broad investigation of the HBV-mediated changes to primary hepatocyte physiology reveals HBV significantly alters metabolic pathways.对 HBV 介导的原代肝细胞生理学变化的广泛研究表明，HBV 显著改变了代谢途径。
Metabolism. 2018 Jun;83:50-59. doi: 10.1016/j.metabol.2018.01.007. Epub 2018 Feb 2.
5
Computational Radiomics System to Decode the Radiographic Phenotype.用于解码影像学表型的计算放射组学系统
Cancer Res. 2017 Nov 1;77(21):e104-e107. doi: 10.1158/0008-5472.CAN-17-0339.
6
Radiomics: Images Are More than Pictures, They Are Data.放射组学：图像不止是图片，它们是数据。
Radiology. 2016 Feb;278(2):563-77. doi: 10.1148/radiol.2015151169. Epub 2015 Nov 18.
7
Mutational landscape of intrahepatic cholangiocarcinoma.肝内胆管癌的突变全景图。
Nat Commun. 2014 Dec 15;5:5696. doi: 10.1038/ncomms6696.
8
Impact of hepatitis B virus infection on outcome following resection for intrahepatic cholangiocarcinoma.乙型肝炎病毒感染对肝内胆管细胞癌切除术后结局的影响。
J Surg Oncol. 2010 Mar 1;101(3):233-8. doi: 10.1002/jso.21488.
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Hepatology. 2004 Jan;39(1):220-9. doi: 10.1002/hep.20031.