• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

慢性偏头痛患者反复枕大神经阻滞与脉冲射频治疗疗效比较:一项随机对照研究。

Comparison of the efficacy of repeated greater occipital nerve block and pulsed radiofrequency therapy in chronic migraine patients: a randomized controlled study.

作者信息

Ertilav Esra, Aydın Osman Nuri

机构信息

Department of Neurology & Algology, Adnan Menderes University Medical Faculty, 09100 Aydin, Turkey.

Department of Anesthesiology & Algology, Adnan Menderes University Medical Faculty, 09100 Aydin, Turkey.

出版信息

J Oral Facial Pain Headache. 2024 Sep;38(3):100-107. doi: 10.22514/jofph.2024.031. Epub 2024 Sep 12.

DOI:10.22514/jofph.2024.031
PMID:39800576
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11810674/
Abstract

The aim of this study was to compare the effectiveness of greater occipital nerve (GON) block and pulsed radiofrequency (PRF) treatment in chronic migraine patients. Seventy patients admitted to the Neurology and Algology outpatient clinic between September 2023 and December 2023 and diagnosed with chronic migraine according to The International Classification of Headache Disorders 3rd Edition (ICHD-3) criteria were included in the study. Patients were randomized into 2 groups to receive ultrasound-guided repeated GON block and PRF. Visual Analog Scale (VAS) scores for pain relief and Migraine Disability Assessment (MIDAS) scores for disability were recorded before the procedure and at 1st and 6th months after the procedure. In both groups, 35 patients with greater occipital nerve (GON) block, 32 patients with GON PRF, the pain scores at 1st and 6th months post-procedure were significantly lower compared to before the procedure ( < 0.001, < 0.001, respectively). VAS scores were significantly lower in the PRF group than in the GON block group at 6th month ( = 0.009). In both groups, post-procedural MIDAS scores at 1st and 6th months were significantly lower compared to before the procedure ( < 0.001, < 0.001, respectively). In the GON PRF group, MIDAS scores at 6th month were significantly lower than MIDAS scores at 1st month ( < 0.001). MIDAS scores were significantly lower in the PRF group compared to the GON block group at 6th months ( < 0.001).Interventional procedures such as GON block and PRF are safe and effective methods in chronic migraine. PRF is a better alternative to GON block in chronic migraine with longer effectiveness.

摘要

本研究的目的是比较枕大神经(GON)阻滞和脉冲射频(PRF)治疗慢性偏头痛患者的有效性。纳入了2023年9月至2023年12月期间在神经科和疼痛门诊就诊、根据《国际头痛疾病分类》第3版(ICHD-3)标准诊断为慢性偏头痛的70例患者。患者被随机分为2组,分别接受超声引导下重复GON阻滞和PRF治疗。在治疗前、治疗后第1个月和第6个月记录视觉模拟量表(VAS)疼痛缓解评分和偏头痛残疾评估(MIDAS)残疾评分。两组中,35例行枕大神经(GON)阻滞,32例行GON PRF,治疗后第1个月和第6个月的疼痛评分均显著低于治疗前(分别为P<0.001,P<0.001)。第6个月时,PRF组的VAS评分显著低于GON阻滞组(P = 0.009)。两组中,治疗后第1个月和第6个月的MIDAS评分均显著低于治疗前(分别为P<0.001,P<0.001)。在GON PRF组中,第6个月的MIDAS评分显著低于第1个月(P<0.001)。第6个月时,PRF组的MIDAS评分显著低于GON阻滞组(P<0.001)。GON阻滞和PRF等介入治疗方法在慢性偏头痛中是安全有效的方法。在慢性偏头痛中,PRF是比GON阻滞更好的选择,其疗效更持久。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c97/11810674/3d7bc038b330/fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c97/11810674/491f685a2f6c/fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c97/11810674/3d7bc038b330/fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c97/11810674/491f685a2f6c/fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c97/11810674/3d7bc038b330/fig2.jpg

相似文献

1
Comparison of the efficacy of repeated greater occipital nerve block and pulsed radiofrequency therapy in chronic migraine patients: a randomized controlled study.慢性偏头痛患者反复枕大神经阻滞与脉冲射频治疗疗效比较:一项随机对照研究。
J Oral Facial Pain Headache. 2024 Sep;38(3):100-107. doi: 10.22514/jofph.2024.031. Epub 2024 Sep 12.
2
Comparison of Two Different Neuromodulation Treatments in Patients With Acute Zoster-Related Trigeminal Neuropathic Pain and Pain Catastrophizing.两种不同神经调节治疗对急性带状疱疹相关性三叉神经痛患者及疼痛灾难化的比较
Neuromodulation. 2025 Jun;28(4):567-574. doi: 10.1016/j.neurom.2025.01.010. Epub 2025 Feb 14.
3
Efficacy of ultrasound-guided greater occipital nerve pulsed radiofrequency therapy in chronic refractory migraine.超声引导下枕大神经脉冲射频治疗慢性难治性偏头痛的疗效
Acta Neurol Belg. 2023 Feb;123(1):191-198. doi: 10.1007/s13760-022-01972-7. Epub 2022 Jun 2.
4
Effectiveness of combining greater occipital nerve block and pulsed radiofrequency treatment in patients with chronic migraine: a double-blind, randomized controlled trial.联合枕大神经阻滞和脉冲射频治疗慢性偏头痛的疗效:一项双盲、随机对照试验。
Head Face Med. 2024 Sep 11;20(1):48. doi: 10.1186/s13005-024-00449-7.
5
Comparative Randomized Study Between Pulsed Radiofrequency and Suprascapular Nerve Block for the Treatment of Chronic Shoulder Pain.脉冲射频与肩胛上神经阻滞治疗慢性肩部疼痛的对比随机研究。
Clin J Pain. 2024 Mar 1;40(3):182-186. doi: 10.1097/AJP.0000000000001184.
6
A new neuromodulation method in chronic migraine; non-ınvasive pulsed radiofrequency, a single-blinded, randomised, controlled trial.一种新的慢性偏头痛神经调节方法;非侵入性脉冲射频,一项单盲、随机、对照试验。
Ir J Med Sci. 2024 Jun;193(3):1487-1493. doi: 10.1007/s11845-023-03598-x. Epub 2023 Dec 26.
7
Prevalence of adverse childhood experiences in the refractory chronic migraine population compared to non-refractory chronic and episodic migraine.难治性慢性偏头痛人群中不良童年经历的患病率与非难治性慢性和发作性偏头痛人群的比较。
Headache. 2025 Jun 20. doi: 10.1111/head.14986.
8
Comparison of two methods of greater occipital nerve block in patients with chronic migraine: ultrasound-guided and landmark-based techniques.两种慢性偏头痛患者枕大神经阻滞方法的比较:超声引导与体表标志定位技术。
BMC Neurol. 2024 Sep 4;24(1):311. doi: 10.1186/s12883-024-03816-8.
9
Noninvasive Vagus Nerve Stimulation for Cluster Headache and Migraine: A Health Technology Assessment.用于丛集性头痛和偏头痛的非侵入性迷走神经刺激:一项卫生技术评估
Ont Health Technol Assess Ser. 2025 May 1;25(2):1-177. eCollection 2025.
10
Regional analgesia techniques for postoperative pain after breast cancer surgery: a network meta-analysis.乳腺癌手术后疼痛的区域镇痛技术:一项网状Meta分析
Cochrane Database Syst Rev. 2025 Jun 4;6(6):CD014818. doi: 10.1002/14651858.CD014818.pub2.

本文引用的文献

1
A new neuromodulation method in chronic migraine; non-ınvasive pulsed radiofrequency, a single-blinded, randomised, controlled trial.一种新的慢性偏头痛神经调节方法;非侵入性脉冲射频,一项单盲、随机、对照试验。
Ir J Med Sci. 2024 Jun;193(3):1487-1493. doi: 10.1007/s11845-023-03598-x. Epub 2023 Dec 26.
2
Efficacy of ultrasound-guided greater occipital nerve pulsed radiofrequency therapy in chronic refractory migraine.超声引导下枕大神经脉冲射频治疗慢性难治性偏头痛的疗效
Acta Neurol Belg. 2023 Feb;123(1):191-198. doi: 10.1007/s13760-022-01972-7. Epub 2022 Jun 2.
3
Pulsed Radiofrequency of the Occipital Nerves: Results of a Standardized Protocol on Chronic Headache Management.
枕神经脉冲射频:慢性头痛管理标准化方案的结果
Anesth Pain Med. 2021 Oct 6;11(5):e112235. doi: 10.5812/aapm.112235. eCollection 2021 Oct.
4
Pulsed Radiofrequency in Interventional Pain Management: Cellular and Molecular Mechanisms of Action - An Update and Review.脉冲射频在介入性疼痛管理中的应用:作用的细胞和分子机制——更新与综述。
Pain Physician. 2021 Dec;24(8):525-532.
5
Effects of Pulsed Radiofrequency on a Standard Model of Muscle Injury in Rats.脉冲射频对大鼠肌肉损伤标准模型的影响。
Anesth Pain Med. 2020 Feb 4;10(1):e97372. doi: 10.5812/aapm.97372. eCollection 2020 Feb.
6
Comparison of two ultrasound-guided techniques for greater occipital nerve injections in chronic migraine: a double-blind, randomized, controlled trial.两种超声引导下技术用于慢性偏头痛中枕大神经注射的比较:一项双盲、随机、对照试验。
Reg Anesth Pain Med. 2019 May;44(5):595-603. doi: 10.1136/rapm-2018-100306. Epub 2019 Mar 18.
7
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness.一项随机、双盲、比较疗效的研究,比较脉冲射频与类固醇注射治疗枕神经痛或伴有枕神经压痛的偏头痛的效果。
Pain. 2015 Dec;156(12):2585-2594. doi: 10.1097/j.pain.0000000000000373.
8
Greater occipital nerve blockade for the treatment of chronic migraine: a randomized, multicenter, double-blind, and placebo-controlled study.枕大神经阻滞治疗慢性偏头痛:一项随机、多中心、双盲、安慰剂对照研究。
Acta Neurol Scand. 2015 Oct;132(4):270-7. doi: 10.1111/ane.12393. Epub 2015 Mar 13.
9
Occipital nerve block for the short-term preventive treatment of migraine: A randomized, double-blinded, placebo-controlled study.枕神经阻滞用于偏头痛的短期预防性治疗:一项随机、双盲、安慰剂对照研究。
Cephalalgia. 2015 Oct;35(11):959-68. doi: 10.1177/0333102414561872. Epub 2014 Dec 12.
10
Chronic migraine prevalence, disability, and sociodemographic factors: results from the American Migraine Prevalence and Prevention Study.慢性偏头痛的患病率、残疾程度和社会人口学因素:来自美国偏头痛患病率和预防研究的结果。
Headache. 2012 Nov-Dec;52(10):1456-70. doi: 10.1111/j.1526-4610.2012.02223.x. Epub 2012 Jul 25.