与志贺氏菌属毒力相关的大质粒具有上皮细胞穿透所必需的共同功能。
Large plasmids associated with virulence in Shigella species have a common function necessary for epithelial cell penetration.
作者信息
Watanabe H, Nakamura A
出版信息
Infect Immun. 1985 Apr;48(1):260-2. doi: 10.1128/iai.48.1.260-262.1985.
Abstract
Large plasmids (120 to 140 megadaltons) associated with virulence of Shigella sonnei, S. flexneri 2a and S. dysenteriae 1 were transferred from each strain into Escherichia coli K-12 and avirulent S. flexneri 1b strains by ampicillin transposon (Tn1)-mediated conduction. Strains with the virulence plasmid could penetrate tissue culture cells irrespective of the original host of the plasmid.
摘要
与宋内志贺菌、福氏志贺菌2a和痢疾志贺菌1型毒力相关的大质粒（120至140兆道尔顿）通过氨苄青霉素转座子（Tn1）介导的传导从每个菌株转移到大肠杆菌K-12和无毒力的福氏志贺菌1b菌株中。携带毒力质粒的菌株能够穿透组织培养细胞，而与质粒的原始宿主无关。
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