Ghaleni Monireh Asadi, Masrour Forouzan Fattahi, Saryar Narjes, Bratty Alexandra J, Norouzi Ebrahim, Fernandes Matheus Santos de Sousa, Badicu Georgian
Department of Motor Behavior, Ferdowsi University of Mashhad, Mashhad, Iran.
Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
AIMS Neurosci. 2024 Oct 12;11(4):421-438. doi: 10.3934/Neuroscience.2024025. eCollection 2024.
Older individuals are at a particular risk of sleep disorders, a loss of cognitive and emotional control, and a poor quality of life. Pharmaceutical therapy for these conditions is commonplace but has not been particularly effective, and relatively little research exists for their treatment using non-pharmacological approaches. The effectiveness of Physical Activity plus selected components of Amygdala and Insula Retraining (PAAIR) was tested to improve sleep quality, depression, working memory, and emotion regulation among older males.
This was a parallel, randomized control trial. The study was conducted in-person among 40 older Iranian men ( : 65.78, = 2.41). The participants were randomly assigned with equal allocation to either the PAAIR or a control condition. Both interventions were conducted in-person over 12 weeks. The participants met twice weekly for 45-minute sessions at a local elderly training and rehabilitation center. All participants completed measurements for sleep quality, depressive symptoms, working memory, and emotion regulation at baseline, 12 weeks (immediately after the intervention), and 8 weeks later.
Among the 36 individuals who finished the study, their sleep quality, working memory, and emotion regulation improved, and their depressive symptoms were reduced from baseline to 12 weeks (post-intervention) and 8 weeks later; these effects were seen even more so for the PAAIR group compared to the control group, with large to extremely large effect sizes.
The findings suggest that PAAIR has the potential to enhance sleep quality, cognitive function, and emotion regulation and reduce depressive symptoms among older men, thus contributing to their quality of life and mental health.
老年人特别容易出现睡眠障碍、认知和情绪控制能力下降以及生活质量不佳的情况。针对这些状况的药物治疗很常见，但效果并不特别显著，而且使用非药物方法进行治疗的研究相对较少。本研究测试了体育活动加杏仁核和脑岛再训练的选定组成部分（PAAIR）对改善老年男性睡眠质量、抑郁、工作记忆和情绪调节的有效性。
这是一项平行随机对照试验。该研究在40名伊朗老年男性（年龄：65.78岁，标准差 = 2.41）中进行了面对面研究。参与者被随机平均分配到PAAIR组或对照组。两种干预措施均在12周内进行了面对面实施。参与者每周在当地的老年培训和康复中心见面两次，每次进行45分钟的课程。所有参与者在基线、12周（干预结束后立即）和8周后完成了睡眠质量、抑郁症状、工作记忆和情绪调节的测量。
在完成研究的36名个体中，他们的睡眠质量、工作记忆和情绪调节得到改善，抑郁症状从基线到12周（干预后）和8周后有所减轻；与对照组相比，PAAIR组的这些效果更为明显，效应量从大到极大。
研究结果表明，PAAIR有可能提高老年男性的睡眠质量、认知功能和情绪调节能力，并减轻抑郁症状，从而有助于提高他们的生活质量和心理健康水平。
