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对参与曼哈顿计划的钚工厂工人进行的37年医学随访。

A 37-year medical follow-up of Manhattan Project Pu workers.

作者信息

Voelz G L, Grier R S, Hempelmann L H

出版信息

Health Phys. 1985 Mar;48(3):249-59. doi: 10.1097/00004032-198503000-00001.

DOI:10.1097/00004032-198503000-00001
PMID:3980212
Abstract

Twenty-six male subjects, who worked with Pu during World War II under extraordinarily crude conditions, have been given medical examinations periodically over the past 37 y to identify potential health effects. Inhalation was the primary mode of the Pu exposures. Current estimates of the systemic Pu depositions in these individuals range from 2 to 95 nCi with a mean of 26 nCi. Seven individuals have depositions of 40 nCi or more, often considered the lifetime maximum permissible body burden for workers. Two individuals have died compared to 6.6 expected deaths based on U.S. adjusted rates for white males. The causes of death were myocardial infarction and accidental trauma. Examinations completed in 1981-82 revealed no cases of cancer in the group except for a history of skin cancers in three individuals. The diseases and physical changes noted in these individuals are characteristic of a male population in their upper 50s or 60s. This study yields no evidence suggesting that adverse health effects have resulted from the 37 y of exposure to internally deposited Pu.

摘要

26名男性受试者在第二次世界大战期间曾在极其简陋的条件下接触钚。在过去37年里,他们定期接受医学检查,以确定潜在的健康影响。吸入是接触钚的主要途径。目前估计这些人体内钚的全身沉积量在2至95纳居里之间,平均为26纳居里。7人的沉积量为40纳居里或更多,这通常被认为是工人的终身最大允许身体负担。与根据美国白人男性调整率预期的6.6例死亡相比,已有2人死亡。死因是心肌梗死和意外创伤。1981年至1982年完成的检查显示,该组除3人有皮肤癌病史外,无癌症病例。这些人身上发现的疾病和身体变化是50多岁或60多岁男性人群的特征。这项研究没有证据表明,37年接触体内沉积的钚会产生不良健康影响。

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