Tanu Felicia P, Perez Mario F, Rathe Tucker V, Mortensen Eric M
Internal Medicine, University of Connecticut School of Medicine, Farmington, USA.
Pulmonary/Critical Care, University of Connecticut Health, Farmington, USA.
Cureus. 2024 Dec 10;16(12):e75498. doi: 10.7759/cureus.75498. eCollection 2024 Dec.
Introduction Despite limited knowledge of its potential health effects, electronic cigarette (e-cigarette) use has become increasingly popular in the United States (US). Cigarette smoking is linked to a higher risk of asthma, and e-cigarettes may have similar effects. This study's aim was to examine the association between e-cigarette use and asthma exacerbations in US adults with known asthma. Methods The 2018 Asthma Call Back Survey (ACBS), paired with corresponding data from the 2018 Behavioral Risk Factor Surveillance System (BRFSS), was utilized for this analysis. Individuals were divided into the following categories: exclusive e-cigarette users, exclusive cigarette users, dual e-cigarette and cigarette users, and never users. A multivariable logistic regression model utilizing a complex survey design was completed after applying weights for population representation and adjusting for potential confounders. Results Of the 11,598 adults in the study, 453 (3.9%) were exclusive e-cigarette users, 3,735 (32.2%) were exclusive cigarette users, 1,484 (12.8%) were dual users, and 5,926 (51.1%) were never users. There was no statistically significant association between asthma exacerbations and exclusive e-cigarette use (OR: 0.88; 95% CI: 0.56-1.38), exclusive cigarette use (OR: 0.80; 95% CI: 0.60-1.05), or dual-use (OR: 0.98; 95% CI: 0.68-1.41). Conclusion There was no association among the categories of exclusive e-cigarette users, exclusive cigarette users, and dual users with asthma exacerbations among adults 18+ with asthma. The results emphasize a need to continue e-cigarette use research to assess future health effects and formulate appropriate public health recommendations.
引言 尽管对电子烟对健康的潜在影响了解有限，但电子烟在美国的使用却日益普遍。吸烟与哮喘风险增加有关，电子烟可能也有类似影响。本研究旨在探讨美国成年哮喘患者中电子烟使用与哮喘发作之间的关联。方法 本分析使用了2018年哮喘回访调查（ACBS）以及2018年行为危险因素监测系统（BRFSS）的相应数据。个体被分为以下几类：仅使用电子烟者、仅使用香烟者、同时使用电子烟和香烟者以及从不使用者。在应用人口代表性权重并对潜在混杂因素进行调整后，完成了采用复杂调查设计的多变量逻辑回归模型。结果 在该研究的11598名成年人中，453人（3.9%）为仅使用电子烟者，3735人（32.2%）为仅使用香烟者，1484人（12.8%）为同时使用者，5926人（51.1%）为从不使用者。哮喘发作与仅使用电子烟（比值比：0.88；95%置信区间：0.56 - 1.38）、仅使用香烟（比值比：0.80；95%置信区间：0.60 - 1.05）或同时使用（比值比：0.98；95%置信区间：0.68 - 1.41）之间无统计学显著关联。结论 在18岁及以上的成年哮喘患者中，仅使用电子烟者、仅使用香烟者和同时使用者这几类人群与哮喘发作之间无关联。研究结果强调有必要继续开展电子烟使用研究，以评估其对未来健康的影响并制定适当的公共卫生建议。
