Rule Payton D, Trammell Victoria L, Hill Patrick L, Pearlstein Jennifer G, Willroth Emily C
Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, MO, USA.
Anesthesiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
Disabil Rehabil. 2025 Jan 13:1-10. doi: 10.1080/09638288.2024.2449392.
PURPOSE/OBJECTIVE: The present review examined the evidence for a potentially bidirectional association between mobility function and cognitive function in midlife and older adulthood.
RESEARCH METHOD/DESIGN: In 2023-2024, we conducted a scoping review by carrying out systematic searches on Google Scholar, PubMed, and PsycINFO for articles that included measures of mobility function and cognitive function.
Of the 1,504 articles screened, 40 were included for review. The majority of reviewed studies found evidence of a relation between lower mobility function/greater mobility decline and lower cognitive function/greater cognitive decline. Prospective effects were observed in both directions; however, only five studies directly tested the bidirectionality of the association between mobility function and cognitive function.
CONCLUSION/IMPLICATIONS: Individuals with lower mobility function may be more likely to experience declines in cognitive function and vice versa. More research is needed to further test the bidirectionality of this association and to identify protective factors that may disrupt this relation and reduce the incidence of co-occurring mobility impairment and cognitive impairment.
目的/目标：本综述探讨了中年及老年人群中运动功能与认知功能之间潜在双向关联的证据。
研究方法/设计：在2023 - 2024年期间，我们通过在谷歌学术、PubMed和PsycINFO上进行系统检索，以查找包含运动功能和认知功能测量指标的文章，从而开展了一项范围综述。
在筛选的1504篇文章中，有40篇被纳入综述。大多数被综述的研究发现了较低运动功能/较大运动功能衰退与较低认知功能/较大认知功能衰退之间存在关联的证据。在两个方向上都观察到了前瞻性效应；然而，只有五项研究直接测试了运动功能与认知功能之间关联的双向性。
结论/启示：运动功能较低的个体可能更易出现认知功能衰退，反之亦然。需要更多研究来进一步测试这种关联的双向性，并确定可能破坏这种关系并降低同时出现运动障碍和认知障碍发生率的保护因素。
