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新型未来牙科材料:抗菌材料“十六烷基氯化吡啶-蒙脱石”和可植入材料“磷酸化普鲁兰多糖”

New future dental material: Antimicrobial material "cetylpyridinium chloride-montmorillonite" and implantable material "phosphorylated pullulan".

作者信息

Nakanishi Ko, Akasaka Tsukasa, Abe Yasuhiko, Hayashi Hiroshi, Yoshihara Kumiko, Nakamura Teppei, Nakamura Mariko, Van Meerbeek Bart, Yoshida Yasuhiro

机构信息

Department of Biomaterials and Bioengineering, Faculty of Dental Medicine, Hokkaido University.

KU Leuven, Department of Oral Health Sciences, BIOMAT & UZ Leuven, Dentistry.

出版信息

Dent Mater J. 2025 Jan 31;44(1):1-8. doi: 10.4012/dmj.2024-243. Epub 2025 Jan 11.

Abstract

In dental practice, there are two major diseases: dental caries and periodontal disease. Although dental treatment techniques have advanced along with advances in dental materials, some diseases such as root surface caries and horizontal bone resorption have not yet achieved satisfactory treatment results. Since these diseases are infections caused by oral bacteria, we believe that materials with long-lasting antimicrobial properties would help control these diseases. In addition, materials that can adhere to wet hard tissues would contribute to treatment. In this review, new materials developed based on this idea, the antimicrobial material "cetylpyridinium chloride-montmorillonite" and the hard tissue adhesive implantable material "phosphorylated pullulan" was introduced.

摘要

在牙科临床中,有两种主要疾病:龋齿和牙周病。尽管牙科治疗技术随着牙科材料的进步而发展,但一些疾病,如根面龋和水平骨吸收,尚未取得令人满意的治疗效果。由于这些疾病是由口腔细菌引起的感染,我们认为具有持久抗菌性能的材料将有助于控制这些疾病。此外,能够粘附于湿润硬组织的材料将有助于治疗。在本综述中,介绍了基于这一理念开发的新材料,即抗菌材料“十六烷基氯化吡啶-蒙脱石”和硬组织粘附性可植入材料“磷酸化普鲁兰多糖”。

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