Martins Rodrigo Prado, Marc Daniel, Germon Pierre, Trapp Sascha, Caballero-Posadas Ignacio
PFIE, INRAE, Nouzilly, France.
ISP, INRAE, Université de Tours, Nouzilly, France.
NPJ Vaccines. 2025 Jan 14;10(1):8. doi: 10.1038/s41541-025-01063-7.
Influenza, a major "One Health" threat, has gained heightened attention following recent reports of highly pathogenic avian influenza in dairy cattle and cow-to-human transmission in the USA. This review explores general aspects of influenza A virus (IAV) biology, its interactions with mammalian hosts, and discusses the key considerations for developing vaccines to prevent or curtail IAV infection in the bovine mammary gland and its spread through milk.
流感是一种主要的“同一健康”威胁，在美国近期报告了奶牛高致病性禽流感以及牛传人病例后，它受到了更多关注。本综述探讨了甲型流感病毒（IAV）生物学的一般方面、其与哺乳动物宿主的相互作用，并讨论了开发疫苗以预防或减少IAV在牛乳腺中的感染及其通过牛奶传播的关键考虑因素。
