Hendricks W M, Swallow R T
J Am Acad Dermatol. 1985 Jan;12(1 Pt 1):90-8. doi: 10.1016/s0190-9622(85)70015-1.
Twenty-one patients with stasis leg ulcers were randomly assigned to two groups. The first group was treated with Unna's boots, while the second was treated with elastic support stockings with graded compression from 24 mm/Hg pressure at the ankle to 16 mm/Hg pressure at the calf. The ulcers on seven of ten legs (70%) treated with Unna's boots and on 10 of 14 legs (71%) treated with elastic support stocking healed. Although the two groups were small, there was no statistically significant difference between their success rate in healing stasis leg ulcers (p = 0.9394). Both treatment groups showed significant changes in lower limb volume, calf circumference, and ankle circumference, although there was no statistically significant difference between the two groups. If healing times are calculated, however, the average healing time in the Unna boot-treated group was 7.3 weeks, while patients treated with support stockings took an average of 18.4 weeks. If one patient whose ulcerations almost encircled her calves and took 78 weeks to heal is excluded, patients treated with support stockings had an average healing time of 11.8 weeks.
21例淤滞性腿部溃疡患者被随机分为两组。第一组采用Unna靴治疗，而第二组采用弹性支撑袜治疗，压力从脚踝处的24毫米汞柱分级递减至小腿处的16毫米汞柱。采用Unna靴治疗的10条腿中有7条（70%）的溃疡愈合，采用弹性支撑袜治疗的14条腿中有10条（71%）的溃疡愈合。尽管两组样本量较小，但它们在淤滞性腿部溃疡愈合成功率上没有统计学显著差异（p = 0.9394）。两个治疗组的下肢体积、小腿周长和脚踝周长均有显著变化，尽管两组之间没有统计学显著差异。然而，如果计算愈合时间，采用Unna靴治疗组的平均愈合时间为7.3周，而采用支撑袜治疗的患者平均需要18.4周。如果排除一名溃疡几乎环绕小腿且愈合时间长达78周的患者，采用支撑袜治疗的患者平均愈合时间为11.8周。
