Arefnia Behrouz, Fakheran Omid, Jakse Norbert, Payer Michael
Division of Restorative Dentistry, Periodontology and Prosthodontics, Department of Dental Medicine and Oral Health, Medical University of Graz, Graz, Austria.
Division of Oral Surgery and Orthodontics, Department of Dental Medicine and Oral Health, Medical University of Graz, Graz, Austria.
J Patient Rep Outcomes. 2025 Jan 14;9(1):7. doi: 10.1186/s41687-025-00839-8.
Zirconia dental implants show excellent biocompatibility and tissue integration, low affinity for plaque, and favorable biomechanical properties. However, these objective measures do not adequately replicate the patient's perception. This systematic review evaluated the evidence on patient-reported outcome (PROs) in zirconia dental implant treatment.
A systematic literature review was conducted following the PRISMA guidelines, utilizing six electronic databases, and supplemented by a manual search of relevant journals and websites to ensure a thorough and comprehensive screening process. The identified studies were subjected to preidentified inclusion criteria. Only controlled clinical trials published in English were considered without limitations on the year of publication. Data on the study characteristics (follow-up, survival rate (%), implant system, number of implants, and type of treatment), PROMs, level of evidence, and Methodological Index for Nonrandomized Studies (MINORS) Bias Score were extracted.
The initial database and hand search yielded 596 articles; 189 were included in the title and abstract screening after excluding the duplicates. Eighteen articles were selected based on the inclusion criteria, among which six were excluded because they did not match the research question. Thus, the final selection comprised 12 articles. Most PROMs (aesthetics, speaking, comfort, chewing ability, and general satisfaction) at prosthetic delivery revealed significantly improved average scores than those at pretreatment.
Despite the respective limitations of the articles included in this systematic review, patients revealed high satisfaction levels with regard to zirconia dental implants. A high level of heterogeneity was observed among the instruments used for measuring the patient-reported outcomes in patients with zirconia implants, thus highlighting the need to develop specific PROMs in the future.
氧化锆牙种植体具有优异的生物相容性和组织整合性，对菌斑的亲和力低，生物力学性能良好。然而，这些客观指标并不能充分反映患者的感受。本系统评价评估了氧化锆牙种植体治疗中患者报告结局（PROs）的相关证据。
按照PRISMA指南进行系统的文献综述，利用六个电子数据库，并辅以对相关期刊和网站的手工检索，以确保全面、综合的筛选过程。纳入的研究需符合预先确定的纳入标准。仅考虑以英文发表的对照临床试验，且对发表年份无限制。提取研究特征（随访、生存率（%）、种植系统、种植体数量和治疗类型）、患者报告结局量表（PROMs）、证据水平和非随机研究方法学指数（MINORS）偏倚评分的数据。
初始数据库和手工检索共获得596篇文章；排除重复项后，189篇文章进入标题和摘要筛选阶段。根据纳入标准选择了18篇文章，其中6篇因不符合研究问题而被排除。最终纳入12篇文章。大多数在修复体交付时的患者报告结局量表（美学、说话、舒适度、咀嚼能力和总体满意度）显示，平均得分比治疗前有显著提高。
尽管本系统评价中纳入的文章存在各自的局限性，但患者对氧化锆牙种植体的满意度较高。在用于测量氧化锆种植体患者报告结局的工具之间观察到高度异质性，因此凸显了未来开发特定患者报告结局量表的必要性。
