Hong Fan, Tan Ronghui, Wang Ting, Zhong Nanshan, Zhao Hongling, Xu Rui-Hua, Shen Lin, Liu Yingbin, Yao Xuebiao, Xiang Dongxi, Hui Lijian, Xiong Jianping, Gao Dong, Zhao Bing, Miao Zhifeng, Hao Jie, Li Yong, Hu Shijun, Fu Boqiang, Hua Guoqiang, Wang Lei, Zeng Zhao-Lei, Chen Chong, Wu Jianmin, Wang Changlin, Wang Chunnian, Zhan Xianbao, Song Chen, Yu Chunping, Yang Yingying, Niu Gengming, Wang Yalong, Zhao Tongbiao, Chen Ye-Guang
Guangzhou National Laboratory, Guangzhou, 510005, China.
The State Key Laboratory of Membrane Biology, Tsinghua‑Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Cell Regen. 2025 Jan 14;14(1):2. doi: 10.1186/s13619-024-00218-6.
Organoid technology provides a transformative approach to understand human physiology and pathology, offering valuable insights for scientific research and therapeutic development. Human gastric organoids, in particular, have gained significant interest for applications in disease modeling, drug discovery, and studies of tissue regeneration and homeostasis. However, the lack of standardized quality control has limited their extensive clinical applications. The "Human Gastric Organoids" is part of a series of guidelines for human gastric organoids in China, which establishes comprehensive standards on terminology, technical specifications, testing methods, inspection rules, usage instructions, labeling, transportation, and storage, developed by experts from the Chinese Society for Cell Biology and its branch societies. Released on October 29, 2024, this guideline aims to establish standardized protocols, enhance institutional practices, and promote international standardization for clinical and research applications of human gastric organoids.
类器官技术为理解人类生理学和病理学提供了一种变革性方法，为科学研究和治疗开发提供了有价值的见解。特别是人类胃类器官，在疾病建模、药物发现以及组织再生和内稳态研究中的应用引起了广泛关注。然而，缺乏标准化的质量控制限制了它们的广泛临床应用。《人类胃类器官》是中国人类胃类器官系列指南的一部分，由中国细胞生物学学会及其分会的专家制定，涵盖了术语、技术规范、检测方法、检验规则、使用说明、标签、运输和储存等方面的全面标准。该指南于2024年10月29日发布，旨在建立标准化方案，加强机构实践，并促进人类胃类器官临床和研究应用的国际标准化。
