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益生菌与食物生物活性成分:揭示它们对肠道微生物群、炎症和代谢健康的影响

Probiotics and Food Bioactives: Unraveling Their Impact on Gut Microbiome, Inflammation, and Metabolic Health.

作者信息

Mafe Alice Njolke, Iruoghene Edo Great, Akpoghelie Patrick Othuke, Gaaz Tayser Sumer, Yousif Emad, Zainulabdeen Khalid, Isoje Endurance Fegor, Igbuku Ufuoma Augustina, Opiti Rapheal Ajiri, Garba Yasal, Essaghah Arthur Efeoghene Athan, Ahmed Dina S, Umar Huzaifa

机构信息

Department of Biological Sciences, Faculty of Science, Taraba State University Jalingo, Jalingo, Taraba State, Nigeria.

Department of Chemistry, Faculty of Science, Delta State University of Science and Technology, Ozoro, Nigeria.

出版信息

Probiotics Antimicrob Proteins. 2025 Jan 14. doi: 10.1007/s12602-025-10452-2.

Abstract

This review paper delves into the role of probiotics and food bioactives in influencing gut health and overall well-being, within the context of probiotics and food bioactives, emphasizing their roles in modulating inflammation, gut microbiota, and metabolic health. Probiotics are defined as live microorganisms that confer health benefits to the host, primarily through their impact on the gut microbiome; a complex community of microorganisms crucial for maintaining health. The review aims to elucidate how probiotics, incorporated into both traditional and modern food systems, can enhance gut health and address metabolic disorders. It examines the types of probiotics present in various foods and their mechanisms of action, including their effects on immune function and metabolic health. By exploring the links between probiotics and health outcomes such as digestive health, immune support, and mental health, the review identifies specific conditions where probiotics show significant promise. Hurldes such as inconsistencies in research findings, variability in probiotic strains, and dosages are addressed. The paper also suggests future research directions, including the potential for personalized probiotic interventions. The review concludes by summarizing key findings and emphasizing the critical role of probiotics in food systems for promoting overall health and mitigating metabolic diseases.

摘要

本综述论文深入探讨了益生菌和食物生物活性成分在影响肠道健康及整体健康方面的作用,结合益生菌和食物生物活性成分的背景,强调它们在调节炎症、肠道微生物群和代谢健康方面的作用。益生菌被定义为能给宿主带来健康益处的活微生物,主要通过其对肠道微生物组的影响来实现;肠道微生物组是维持健康至关重要的复杂微生物群落。该综述旨在阐明纳入传统和现代食品体系的益生菌如何能增强肠道健康并解决代谢紊乱问题。它研究了各种食物中存在的益生菌类型及其作用机制,包括它们对免疫功能和代谢健康的影响。通过探索益生菌与消化健康、免疫支持和心理健康等健康结果之间的联系,该综述确定了益生菌显示出显著前景的特定情况。研究结果不一致、益生菌菌株和剂量的可变性等障碍也得到了探讨。本文还提出了未来的研究方向,包括个性化益生菌干预的潜力。综述最后总结了关键发现,并强调了益生菌在食品体系中对促进整体健康和缓解代谢疾病的关键作用。

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