Mafe Alice N, Büsselberg Dietrich
Department of Biological Sciences, Faculty of Sciences, Taraba State University, Main Campus, Jalingo 660101, Taraba State, Nigeria.
Weill Cornell Medicine-Qatar, Education City, Qatar Foundation, Doha Metropolitan Area P.O. Box 22104, Qatar.
Foods. 2024 Dec 1;13(23):3886. doi: 10.3390/foods13233886.
Foodborne pathogens are microorganisms that cause illness through contamination, presenting significant risks to public health and food safety. This review explores the metabolites produced by these pathogens, including toxins and secondary metabolites, and their implications for human health, particularly concerning cancer risk. We examine various pathogens such as sp., sp., , and , detailing the specific metabolites of concern and their carcinogenic mechanisms. This study discusses analytical techniques for detecting these metabolites, such as chromatography, spectrometry, and immunoassays, along with the challenges associated with their detection. This study covers effective control strategies, including food processing techniques, sanitation practices, regulatory measures, and emerging technologies in pathogen control. This manuscript considers the broader public health implications of pathogen metabolites, highlighting the importance of robust health policies, public awareness, and education. This review identifies research gaps and innovative approaches, recommending advancements in detection methods, preventive strategies, and policy improvements to better manage the risks associated with foodborne pathogens and their metabolites.
食源性病原体是通过污染导致疾病的微生物,对公众健康和食品安全构成重大风险。本综述探讨了这些病原体产生的代谢产物,包括毒素和次级代谢产物,及其对人类健康的影响,特别是与癌症风险相关的影响。我们研究了各种病原体,如 、 、 和 ,详细阐述了相关的特定代谢产物及其致癌机制。本研究讨论了检测这些代谢产物的分析技术,如色谱法、光谱法和免疫测定法,以及与检测相关的挑战。本研究涵盖了有效的控制策略,包括食品加工技术、卫生措施、监管措施以及病原体控制方面的新兴技术。本手稿考虑了病原体代谢产物对更广泛的公众健康的影响,强调了强有力的健康政策、公众意识和教育的重要性。本综述确定了研究差距和创新方法,建议在检测方法、预防策略和政策改进方面取得进展,以更好地管理与食源性病原体及其代谢产物相关的风险。