Ozbir Sait, Girgin Mehmet Cengiz, Kara Cengiz, Dincel Cetin
Department of 1st Urology, Izmir Ataturk Training and Research Hospital, Izmir, Turkey.
Clin Pract. 2011 Jul 1;1(3):e47. doi: 10.4081/cp.2011.e47.
Schwannomas are usually benign rare tumors that originating from Schwann cells of peripheral nerve sheaths. Presentation is generally varied and changed in a non-specific range from abdominal mass, flank pain to incidental findings. Herein we report 2 cases of retroperitoneal giant schwannomas with different clinical presentations, of whom one presented with vague abdominal pain, palpable abdominal mass for 4 years, swelling and bilateral hydronephrosis that caused by giant abdominal mass; the other one presented with right flank pain, rectal hemorrhage and lower extremities edema. Two patients were treated by complete surgical excision of masses. The histological and immunohistochemical diagnosis was reported as benign schwannoma. Both of patients are doing well and had no recurrence in 9 years and 28 months follow-up, respectively.
施万细胞瘤通常是起源于周围神经鞘雪旺细胞的良性罕见肿瘤。临床表现通常多样，范围从腹部肿块、胁腹疼痛到偶然发现，无特异性。在此，我们报告2例具有不同临床表现的腹膜后巨大施万细胞瘤，其中1例表现为腹部隐痛、可触及腹部肿块4年，巨大腹部肿块导致肿胀和双侧肾积水；另一例表现为右侧胁腹疼痛、直肠出血和下肢水肿。两名患者均通过完整手术切除肿块进行治疗。组织学和免疫组化诊断为良性施万细胞瘤。两名患者情况良好，分别在9年和28个月的随访中均无复发。
