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静脉血栓栓塞病史是否应被视为水肺潜水的禁忌症?

Should a history of venous thromboembolism be considered a contraindication for scuba diving?

作者信息

Vannini Mathilde, Schved Jean-François, Smadja David M, Jung Viktoria E M, Mauge Laetitia, Sanchez Olivier, Gendron Nicolas

机构信息

Hematology Department, Assistance Publique - Hôpitaux de Paris-Centre Université de Paris, Paris, France.

Université de Montpellier, Montpellier, France.

出版信息

Res Pract Thromb Haemost. 2024 Dec 2;9(1):102647. doi: 10.1016/j.rpth.2024.102647. eCollection 2025 Jan.

DOI:10.1016/j.rpth.2024.102647
PMID:39810982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11729648/
Abstract

The question of whether scuba diving is safe for patients with a history of venous thromboembolism (VTE) remains unanswered. Cases of VTE have been reported after decompression accidents but not following properly conducted dives. However, the risk of VTE and bleeding on anticoagulant therapy during diving has yet to be defined. Medical diving societies make different recommendations regarding the risk of scuba diving in patients with a history of VTE and/or hereditary thrombophilia and regarding the bleeding risk under anticoagulation associated with dives. There is no epidemiologic or pathophysiologic evidence described in the literature to support a direct association between VTE and diving. Therefore, VTE cannot be considered as a definite contraindication for scuba diving. Further studies are needed to conclusively establish the risk of VTE associated with diving and to guide the development of medical guidelines by diving societies.

摘要

有静脉血栓栓塞(VTE)病史的患者进行水肺潜水是否安全这一问题仍未得到解答。减压事故后曾有VTE病例报告,但正常潜水后未出现此类情况。然而,潜水期间接受抗凝治疗时发生VTE和出血的风险尚未明确。医学潜水协会对于有VTE病史和/或遗传性血栓形成倾向的患者进行水肺潜水的风险以及与潜水相关的抗凝状态下的出血风险给出了不同建议。文献中未描述有流行病学或病理生理学证据支持VTE与潜水之间存在直接关联。因此,不能将VTE视为水肺潜水的绝对禁忌证。需要进一步研究来最终确定与潜水相关的VTE风险,并指导潜水协会制定医学指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87c1/11729648/ec4d49314837/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87c1/11729648/ec4d49314837/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87c1/11729648/ec4d49314837/ga1.jpg

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本文引用的文献

1
Iatrogenic air embolism: pathoanatomy, thromboinflammation, endotheliopathy, and therapies.医源性空气栓塞:病理解剖学、血栓炎症、血管内皮病变和治疗方法。
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Portal and Mesenteric Vein Thrombosis Associated with Decompression Sickness in a 48-Year-Old Deep Sea Self-Contained Underwater Breathing Apparatus (SCUBA) Diver.48 岁深海自给式水下呼吸装置(SCUBA)潜水员减压病并发门静脉和肠系膜静脉血栓形成。
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White Blood Cells, Platelets, Red Blood Cells and Gas Bubbles in SCUBA Diving: Is There a Relationship?
水肺潜水中的白细胞、血小板、红细胞与气泡:它们之间存在关联吗?
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Eur Heart J. 2020 Jan 21;41(4):543-603. doi: 10.1093/eurheartj/ehz405.
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Rev Mal Respir. 2019 Feb;36(2):249-283. doi: 10.1016/j.rmr.2019.01.003. Epub 2019 Feb 22.
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