Orenstein D M, Reed M E, Grogan F T, Crawford L V
J Pediatr. 1985 Apr;106(4):556-60. doi: 10.1016/s0022-3476(85)80071-8.
A controlled study of 20 children with asthma who participated in a 4-month running program (30 min/day, 3 days/wk), using inhalation of a beta-2 stimulant prior to each running session to prevent exercise-induced asthma, showed significant increases in work tolerance (120.5 +/- 45.0 W before, 131.5 +/- 43.5 W after, P = 0.002) and cardiopulmonary fitness (peak oxygen consumption 37.6 +/- 8.6 ml/kg/min before, 43.1 +/- 10.5 ml/kg/min after, P less than 0.001). Asthma severity judged by daily asthma diary scores and twice daily peak flows did not change. Thirteen control patients with asthma did not exercise and demonstrated no change in work tolerance, fitness, or severity of asthma. Thus, children with asthma can safely engage in a running program and can increase work tolerance and fitness without worsening their asthma.
一项针对20名哮喘儿童的对照研究，这些儿童参加了为期4个月的跑步计划（每天30分钟，每周3天），在每次跑步前吸入β-2兴奋剂以预防运动诱发的哮喘。研究显示，工作耐力显著提高（之前为120.5±45.0瓦，之后为131.5±43.5瓦，P = 0.002），心肺适能也显著提高（峰值耗氧量之前为37.6±8.6毫升/千克/分钟，之后为43.1±10.5毫升/千克/分钟，P＜0.001）。通过每日哮喘日记评分和每日两次的峰值呼气流速判断的哮喘严重程度没有变化。13名未运动的哮喘对照患者在工作耐力、适能或哮喘严重程度方面没有变化。因此，哮喘儿童可以安全地参与跑步计划，并且能够在不加重哮喘病情的情况下提高工作耐力和适能。
