Ram F S, Robinson S M, Black P N
Department of Medicine, School of Medicine, University of Auckland, New Zealand.
Br J Sports Med. 2000 Jun;34(3):162-7. doi: 10.1136/bjsm.34.3.162.
To assess the evidence for the effects of physical training on pulmonary function, symptoms, cardiopulmonary fitness, and quality of life in subjects with asthma.
A search was conducted for randomised controlled trials of subjects with asthma undertaking physical training using the Cochrane Airways Group register of controlled clinical trials, Medline, Embase, Sportdiscus, Science citation index, and Current contents index. Studies were included in the review if the subjects had asthma, were 8 years of age or older, and had undertaken physical training for at least 20 minutes per session, twice a week, for a minimum of four weeks. The eligibility of trials for inclusion in the review and the quality of the trials were independently assessed by two reviewers.
Eight studies with a total of 226 subjects met the inclusion criteria for this review. Physical training had no effect on resting lung function but led to an improvement in cardiopulmonary fitness as measured by an increase in maximum oxygen uptake of 5.6 ml/kg/min (95% confidence interval 3.9 to 7.2). None of the studies measured quality of life.
Physical training improves cardiopulmonary fitness without changing lung function. It is not clear if the improvement in fitness translates into a reduction in symptoms or an improvement in the quality of life. There is a need for further randomised controlled trials of the effects of physical training in the management of asthma.
评估体育锻炼对哮喘患者肺功能、症状、心肺适能及生活质量影响的证据。
使用Cochrane气道组对照临床试验注册库、医学期刊数据库（Medline）、荷兰医学文摘数据库（Embase）、体育科学数据库（Sportdiscus）、科学引文索引及现刊目次索引，检索有关哮喘患者进行体育锻炼的随机对照试验。如果受试者患有哮喘、年龄在8岁或以上，且每次锻炼至少20分钟、每周两次、持续至少四周，则纳入本综述研究。两名评审员独立评估纳入综述的试验的合格性及试验质量。
八项研究共226名受试者符合本综述的纳入标准。体育锻炼对静息肺功能无影响，但通过最大摄氧量增加5.6毫升/千克/分钟（95%置信区间3.9至7.2）衡量，可改善心肺适能。没有一项研究测量生活质量。
体育锻炼可改善心肺适能而不改变肺功能。尚不清楚适能的改善是否能转化为症状减轻或生活质量提高。需要进一步进行体育锻炼对哮喘管理影响的随机对照试验。
