Primaputra Muhammad Ra, Malau Vino D, Budhy Filberto, Yudhistira Pramudito
Department of Orthopedic dan Traumatology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Narra J. 2024 Dec;4(3):e1115. doi: 10.52225/narra.v4i3.1115. Epub 2024 Oct 30.
Synovial chondromatosis is a rare disorder characterized by cartilaginous growths within the joint lining, often confused with conditions like pigmented villonodular synovitis and rheumatoid arthritis. Primary treatment typically involves surgical synovectomy to remove the affected tissue and loose bodies. Documented cases are limited globally. The aim of this study was to present a case series of synovial chondromatosis and evaluate the functional outcomes by assessing the post-surgical Musculoskeletal Tumor Society (MSTS) score following different surgical interventions (synovectomy alone versus synovectomy with total knee replacement) in a resource-limited setting. Four cases of synovial chondromatosis were reported. A 61-year-old woman with a soft tissue tumor underwent synovectomy and total knee replacement on the right knee, then experienced a periprosthetic infection requiring revision arthroplasty, resulting in an MSTS score of 24. Another case was a 48-year-old woman who had a synovectomy for a lump on the right knee, also achieving an MSTS score of 24. Two additional cases involved women in their mid-to-late 60s who underwent synovectomy for knee lumps, with post-operative MSTS scores of 21 and 19, respectively. This case series underscores the diagnostic and management challenges of synovial chondromatosis in the knee joint, demonstrating various surgical interventions. This case series also suggested that the post-operative MSTS scores were slightly higher (indicating better outcomes) for synovectomy alone compared to synovectomy with total knee replacement, highlighting the need for further research to determine the most effective treatment approach.
滑膜软骨瘤病是一种罕见的疾病，其特征是关节衬里内出现软骨生长，常与色素沉着绒毛结节性滑膜炎和类风湿性关节炎等疾病相混淆。主要治疗方法通常包括手术滑膜切除术，以切除受影响的组织和游离体。全球范围内记录在案的病例有限。本研究的目的是呈现一组滑膜软骨瘤病病例，并在资源有限的环境中，通过评估不同手术干预（单纯滑膜切除术与全膝关节置换术联合滑膜切除术）后的术后肌肉骨骼肿瘤学会（MSTS）评分，来评估功能结果。报告了4例滑膜软骨瘤病病例。一名61岁患有软组织肿瘤的女性接受了右膝关节滑膜切除术和全膝关节置换术，随后发生假体周围感染，需要进行翻修关节成形术，MSTS评分为24分。另一例是一名48岁女性，因右膝肿块接受了滑膜切除术，MSTS评分也为24分。另外两例涉及60多岁中后期的女性，她们因膝部肿块接受了滑膜切除术，术后MSTS评分分别为21分和19分。该病例系列强调了膝关节滑膜软骨瘤病的诊断和管理挑战，展示了各种手术干预方法。该病例系列还表明，与全膝关节置换术联合滑膜切除术相比，单纯滑膜切除术的术后MSTS评分略高（表明结果更好），突出了需要进一步研究以确定最有效的治疗方法。
