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开始性别确认激素治疗24个月后的跨性别青少年的情绪健康

Emotional Health of Transgender Youth 24 Months After Initiating Gender-Affirming Hormone Therapy.

作者信息

Olson-Kennedy Johanna, Wang Liyuan, Wong Carolyn F, Chen Diane, Ehrensaft Diane, Hidalgo Marco A, Tishelman Amy C, Chan Yee-Ming, Garofalo Robert, Radix Asa E, Rosenthal Stephen M

机构信息

Division of Adolescent and Young Adult Medicine, Children's Hospital, Los Angeles, California; Department of Pediatrics, University of Southern California, Los Angeles, California.

Department of Health Promotion and Behavior, University of Georgia, College of Public Health, Athens, Georgia.

出版信息

J Adolesc Health. 2025 Jul;77(1):41-50. doi: 10.1016/j.jadohealth.2024.11.014. Epub 2025 Jan 16.

Abstract

PURPOSE

Limited data exist about the emotional health of transgender youth, either before or after initiation of gender-affirming hormone (GAH). The objectives were: (1) Investigate and verify the factor structure of the National Institutes of Health Toolbox Emotional Battery (NIHTB-EB) among trans and non-binary (TNB) youth; (2) Examine changes in emotional health over 24 months of GAH treatment; and (3) Examine the extent to which changes in emotional health were associated with improved appearance congruence (AC).

METHODS

Study respondents were from Trans Youth Care - United States (TYCUS) study, an observational, prospective, longitudinal study of adolescents initiating GAH enrolled between 2016 and 2019. Data were obtained at baseline, 6, 12, 18 and 24 months following initiation of GAHtreatment. Participants were receiving services at one of the 4 study sites. Eligible participants were those with gender dysphoria, aged 12-20 years, naïve to GAH, and initiating GAH for the purpose of phenotypic gender transition.

RESULTS

315 youth aged 12-20 years (M = 16.1, SD = 1.87) were predominantly White (58.7%) and transmasculine (65%). Factor analysis of the NIHTB-EB measures yielded 4 emotional health dimensions, consistent with prior studies of other cohorts. Over the observation period, participants demonstrated significant improvements in AC, psychological well-being, social satisfaction and self-efficacy and significant reductions in negative affect and negative social perception. Significant associations between AC and different indicators of emotional functioning were observed at baseline and over time.

DISCUSSION

Emotional functioning after 24 months of GAH treatment significantly improved and was associated with an improvement in AC.

摘要

目的

关于跨性别青少年在开始接受性别确认激素(GAH)治疗之前或之后的情绪健康状况,现有数据有限。本研究的目标是:(1)调查并验证美国国立卫生研究院工具箱情绪量表(NIHTB-EB)在跨性别和非二元性别(TNB)青少年中的因子结构;(2)研究GAH治疗24个月期间情绪健康状况的变化;(3)探讨情绪健康状况的变化与外貌一致性(AC)改善之间的关联程度。

方法

研究参与者来自美国跨性别青少年关爱研究(TYCUS),这是一项对2016年至2019年间开始接受GAH治疗的青少年进行的观察性、前瞻性纵向研究。在开始GAH治疗后的基线、6个月、12个月、18个月和24个月收集数据。参与者在4个研究地点之一接受服务。符合条件的参与者为患有性别焦虑症、年龄在12至20岁之间、未接受过GAH治疗且为了表型性别转变而开始接受GAH治疗的青少年。

结果

315名年龄在12至20岁之间(M = 16.1,SD = 1.87)的青少年中,白人占多数(58.7%),且以跨性别男性为主(65%)。对NIHTB-EB量表进行因子分析得出了4个情绪健康维度,与其他队列的先前研究结果一致。在观察期内,参与者的AC、心理健康、社会满意度和自我效能感均有显著改善,负面影响和负面社会认知显著降低。在基线和随访期间均观察到AC与情绪功能不同指标之间存在显著关联。

讨论

GAH治疗24个月后的情绪功能显著改善,且与AC的改善相关。

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