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优化中亚地区的抗生素管理并减少抗菌药物耐药性:一项基于证据的实践与政策研究方案

Optimizing antibiotic stewardship and reducing antimicrobial resistance in Central Asia: A study protocol for evidence-based practice and policy.

作者信息

Lim Lisa, Kassym Laura, Kussainova Assiya, Aubakirova Bibigul, Semenova Yuliya

机构信息

Nazarbayev University, Astana, Kazakhstan.

Astana Medical University, Astana, Kazakhstan.

出版信息

PLoS One. 2025 Jan 16;20(1):e0307784. doi: 10.1371/journal.pone.0307784. eCollection 2025.

Abstract

Antimicrobial resistance (AMR) poses a significant global health challenge, prompting the World Health Organization (WHO) to stress the importance of monitoring antibiotic consumption and sales to address AMR effectively. This study protocol aims to optimize antibiotic stewardship and combat AMR in Central Asia through evidence-based practices and policies. The protocol includes objectives such as conducting systematic reviews of interventions to promote judicious antibiotic use, assessing antibiotic consumption trends, and investigating antibiotic overuse practices among healthcare providers. The study aims to raise awareness among stakeholders to enhance appropriate antibiotic prescribing practices. By establishing regulatory frameworks, monitoring policies' effectiveness, and providing training programs for healthcare professionals, this study seeks to contribute to the global efforts in combating AMR and promoting prudent antibiotic use.

摘要

抗菌药物耐药性(AMR)对全球健康构成了重大挑战,促使世界卫生组织(WHO)强调监测抗生素消费和销售对于有效应对AMR的重要性。本研究方案旨在通过循证实践和政策优化中亚地区的抗生素管理并对抗菌药物耐药性。该方案包括以下目标:对促进合理使用抗生素的干预措施进行系统评价、评估抗生素消费趋势以及调查医疗服务提供者中的抗生素过度使用情况。该研究旨在提高利益相关者的认识,以加强适当的抗生素处方行为。通过建立监管框架、监测政策有效性以及为医疗专业人员提供培训项目,本研究力求为全球抗击抗菌药物耐药性和促进谨慎使用抗生素的努力做出贡献。

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