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优化中亚地区的抗生素管理并减少抗菌药物耐药性:一项基于证据的实践与政策研究方案

Optimizing antibiotic stewardship and reducing antimicrobial resistance in Central Asia: A study protocol for evidence-based practice and policy.

作者信息

Lim Lisa, Kassym Laura, Kussainova Assiya, Aubakirova Bibigul, Semenova Yuliya

机构信息

Nazarbayev University, Astana, Kazakhstan.

Astana Medical University, Astana, Kazakhstan.

出版信息

PLoS One. 2025 Jan 16;20(1):e0307784. doi: 10.1371/journal.pone.0307784. eCollection 2025.

DOI:10.1371/journal.pone.0307784
PMID:39820801
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11737725/
Abstract

Antimicrobial resistance (AMR) poses a significant global health challenge, prompting the World Health Organization (WHO) to stress the importance of monitoring antibiotic consumption and sales to address AMR effectively. This study protocol aims to optimize antibiotic stewardship and combat AMR in Central Asia through evidence-based practices and policies. The protocol includes objectives such as conducting systematic reviews of interventions to promote judicious antibiotic use, assessing antibiotic consumption trends, and investigating antibiotic overuse practices among healthcare providers. The study aims to raise awareness among stakeholders to enhance appropriate antibiotic prescribing practices. By establishing regulatory frameworks, monitoring policies' effectiveness, and providing training programs for healthcare professionals, this study seeks to contribute to the global efforts in combating AMR and promoting prudent antibiotic use.

摘要

抗菌药物耐药性(AMR)对全球健康构成了重大挑战,促使世界卫生组织(WHO)强调监测抗生素消费和销售对于有效应对AMR的重要性。本研究方案旨在通过循证实践和政策优化中亚地区的抗生素管理并对抗菌药物耐药性。该方案包括以下目标:对促进合理使用抗生素的干预措施进行系统评价、评估抗生素消费趋势以及调查医疗服务提供者中的抗生素过度使用情况。该研究旨在提高利益相关者的认识,以加强适当的抗生素处方行为。通过建立监管框架、监测政策有效性以及为医疗专业人员提供培训项目,本研究力求为全球抗击抗菌药物耐药性和促进谨慎使用抗生素的努力做出贡献。

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本文引用的文献

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Antimicrobial Resistance: A Growing Serious Threat for Global Public Health.抗菌药物耐药性:对全球公共卫生日益严重的威胁。
Healthcare (Basel). 2023 Jul 5;11(13):1946. doi: 10.3390/healthcare11131946.
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Factors Influencing Antibiotic Consumption in Adult Population of Kazakhstan.影响哈萨克斯坦成年人口抗生素消费的因素
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Factors Influencing the Implementation of Antimicrobial Stewardship in Primary Care: A Narrative Review.影响基层医疗中抗菌药物管理实施的因素:一项叙述性综述
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Ann Ist Super Sanita. 2022 Jul-Sep;58(3):204-212. doi: 10.4415/ANN_22_03_10.
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Global antibiotic consumption and usage in humans, 2000-18: a spatial modelling study.全球人类抗生素消费与使用量,2000-2018 年:空间建模研究。
Lancet Planet Health. 2021 Dec;5(12):e893-e904. doi: 10.1016/S2542-5196(21)00280-1. Epub 2021 Nov 12.
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JAC Antimicrob Resist. 2019 Nov 12;1(3):dlz072. doi: 10.1093/jacamr/dlz072. eCollection 2019 Dec.
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Healthcare workers' knowledge, attitudes and behaviours with respect to antibiotics, antibiotic use and antibiotic resistance across 30 EU/EEA countries in 2019.2019 年,30 个欧盟/欧洲经济区国家的医护人员在抗生素、抗生素使用和抗生素耐药性方面的知识、态度和行为。
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Anticipating the Need for Healthcare Resources Following the Escalation of the COVID-19 Outbreak in the Republic of Kazakhstan.哈萨克斯坦共和国新冠疫情升级后对医疗资源需求的预测
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