Kumar Rahul, Tamizhan Sudhahar, Darbari Anshuman, Naithani Manisha, Malik Saloni, Yadav Nisha, Saini Ankit
Department of Biochemistry, AIIMS Rishikesh, Rishikesh, Uttarakhand 249203 India.
CTVS Department, AIIMS Rishikesh, Rishikesh, 249203 India.
Indian J Thorac Cardiovasc Surg. 2025 Feb;41(2):167-174. doi: 10.1007/s12055-024-01850-2. Epub 2024 Nov 8.
Testing methods of detecting various cardiac biomarkers play a significant influence in determining and treating cardiac-related conditions and ultimate prognosis. With the increasing global prevalence of cardiac disease, the importance of rapid testing methods in diagnosis and management has grown tremendously. The point-of-care testing (POCT) method is a potential biochemical diagnostic technique that may overcome the issue of delayed laboratory results, particularly in regions with limited access to advanced laboratory equipment or resource-constrained. Point-of-care (POC) diagnostics are also a user-friendly method and may be easily utilised by laboratory personnel and other healthcare professionals with fundamental basic training in remote areas where specialised laboratories may be challenging to access. Another recent development is of various biosensors with incorporation of artificial intelligence (AI) technology to give early test results that may enable immediate clinical decisions, thereby enhancing the patient's health outcomes. This narrative review has been done with the aim of enhancing knowledge for current POCT methods, their diagnostic role in major cardiac ailments, comparison with other standard methods with ongoing clinical trials, and future developments. Information for this review article has been gathered and compiled by searching major databases on the internet with recent clinical trials and assessed on the Scale for the Assessment of Narrative Review Articles (SANRA) to present here.
The online version contains supplementary material available at 10.1007/s12055-024-01850-2.
检测各种心脏生物标志物的检测方法在确定和治疗心脏相关疾病及最终预后方面具有重大影响。随着全球心脏病患病率的不断上升,快速检测方法在诊断和管理中的重要性已大幅提高。即时检验(POCT)方法是一种潜在的生化诊断技术,它可能克服实验室结果延迟的问题,特别是在难以获得先进实验室设备或资源有限的地区。即时诊断(POC)也是一种用户友好的方法,在难以进入专业实验室的偏远地区,经过基本培训的实验室人员和其他医疗专业人员可以轻松使用。最近的另一项进展是各种生物传感器结合了人工智能(AI)技术,能够给出早期检测结果,从而可以立即做出临床决策,进而改善患者的健康结局。本叙述性综述旨在增进对当前POCT方法、其在主要心脏疾病中的诊断作用、与其他标准方法的比较以及正在进行的临床试验和未来发展的了解。本文的信息是通过搜索互联网上的主要数据库并结合近期临床试验收集和整理的,并根据叙述性综述文章评估量表(SANRA)进行评估后在此呈现。
在线版本包含可在10.1007/s12055-024-01850-2获取的补充材料。