Hong Yi, Huang He, Zhang Zizhen, Wang Xuguo, Liu Huaqing, Meng Xiangying, Dong Xingqiang, Zhu Feng, Bai Zhenjiang, Lu Meihua, Wu Shuiyan, Jiang Wei, Lu Yanhong
Pediatric Intensive Care Unit, Children Hospital of Soochow University, Suzhou, China.
Department of Pediatrics, Changshu Hospital Affiliated to Nanjing University of Chinese Medicine, Suzhou, China.
Transl Pediatr. 2024 Dec 31;13(12):2155-2163. doi: 10.21037/tp-24-281. Epub 2024 Dec 27.
It has been reported that the emergence of coronavirus disease 2019 (COVID-19) has changed the epidemiological characteristics of many pathogens, but the epidemiological characteristics of (MP) infection in hospitalized children with community-acquired pneumonia (CAP) are not clear. The aim of this study was to answer this question.
Children with CAP in three tertiary hospitals (hospitals A, B and C) from 2018 to 2023 were selected. Data on gender, age, number and date of MP infection were obtained from the medical record. The intensity of the epidemic was measured as a percentage of the number of CAP.
In hospitals A and B, before the pandemic (in 2018 and 2019), the number of hospitalized children with MP pneumonia and the proportion of total pneumonia had shown a significant upward trend, but the control measures led to a slight decline. In hospital C, the number and percentage of hospitalized children with MP pneumonia were low before and during the COVID-19 period. After the epidemic control was lifted, the number and percentage of children with MP pneumonia in the three hospitals increased sharply, and the proportion of children aged more than 7 years old increased significantly in 2022 and 2023.
From 2018 to 2019, there was already an epidemic trend of MP in the study hospital. From 2020 to 2022, after the outbreak of COVID-19, the incidence of MP pneumonia stabilized, but after the epidemic control was lifted, it broke out. This may be due to the severe restrictive measures taken early during the COVID-19 pandemic that effectively controlled the spread of MP, pausing its pandemic.
据报道，2019冠状病毒病（COVID-19）的出现改变了许多病原体的流行病学特征，但社区获得性肺炎（CAP）住院儿童中肺炎支原体（MP）感染的流行病学特征尚不清楚。本研究旨在回答这一问题。
选取2018年至2023年三家三级医院（A、B、C医院）的CAP患儿。从病历中获取性别、年龄、MP感染次数和日期等数据。以CAP病例数的百分比来衡量流行强度。
在A医院和B医院，在大流行之前（2018年和2019年），MP肺炎住院儿童数量及占总肺炎的比例呈显著上升趋势，但控制措施使其略有下降。在C医院，COVID-19期间及之前MP肺炎住院儿童数量和百分比均较低，但疫情防控解除后，三家医院MP肺炎患儿数量和百分比均急剧增加，2022年和2023年7岁以上儿童的比例显著增加。
2018年至2019年，研究医院已有MP流行趋势。2020年至2022年，COVID-19疫情爆发后，MP肺炎发病率稳定，但疫情防控解除后爆发。这可能是由于COVID-19大流行早期采取的严格限制措施有效控制了MP的传播，使其流行暂停。
