重症肌无力患者骨髓细胞产生乙酰胆碱受体抗体的情况。
Acetylcholine receptor antibody production by bone marrow cells in a patient with myasthenia gravis.
作者信息
Fujii Y, Monden Y, Hashimoto J, Nakahara K, Kawashima Y
出版信息
Neurology. 1985 Apr;35(4):577-9. doi: 10.1212/wnl.35.4.577.
PMID:3982648
Abstract
We briefly report antiacetylcholine receptor antibody production by cultured bone marrow cells (4.9 +/- 0.9 fmol/10(6) cells/wk, mean +/- SD) in a 65-year-old man with myasthenia gravis without thymoma. Lymphocytes from peripheral blood, thymus, and lymph nodes produced less antibody (1.8 +/- 0.1, 0.9 +/- 0.3, and 1.0 +/- 0.4, respectively). The thymus was involuted, and the effect of thymectomy was doubtful 6 months postoperatively.
摘要
我们简要报告了一名65岁无胸腺瘤的重症肌无力男性患者，其培养的骨髓细胞可产生抗乙酰胆碱受体抗体（4.9±0.9飞摩尔/10⁶细胞/周，均值±标准差）。外周血、胸腺和淋巴结中的淋巴细胞产生的抗体较少（分别为1.8±0.1、0.9±0.3和1.0±0.4）。胸腺已萎缩，术后6个月胸腺切除术的效果存疑。
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