Wakui M, Inomata H
Pflugers Arch. 1985 Jan;403(1):109-11. doi: 10.1007/BF00583290.
The electrical response of the smooth muscle of guinea-pig vas deferens to exogenously applied noradrenaline (NA) was examined using the double sucrose-gap method. NA evoked a depolarization of the smooth muscle membrane which was associated with an increase in the size of electrotonic potentials. A conditioning depolarization of the membrane induced by current application enhanced the size of NA-induced depolarization, whereas a conditioning hyperpolarization reduced it. When a conditioning hyperpolarization of 25 mV in magnitude was applied, the direction of potential change induced by NA was reversed. These results are discussed with respect to the ionic mechanism of the electrical event in response to NA in this tissue.
采用双蔗糖间隙法研究了豚鼠输精管平滑肌对外源性去甲肾上腺素（NA）的电反应。NA引起平滑肌膜去极化，这与电紧张电位大小的增加有关。通过施加电流诱导的膜条件性去极化增强了NA诱导的去极化大小，而条件性超极化则使其减小。当施加幅度为25mV的条件性超极化时，NA诱导的电位变化方向发生逆转。针对该组织中对NA反应的电事件的离子机制对这些结果进行了讨论。
