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在一个不进行反射性HIV RNA检测的南方选择退出式HIV检测环境中,急性人类免疫缺陷病毒(HIV)感染的漏诊和延迟诊断情况。

Missed and Delayed Diagnoses of Acute Human Immunodeficiency Virus (HIV) Infection in a Southern Opt-Out HIV Testing Environment Without Reflex HIV RNA Testing.

作者信息

Gruber Sarah F, Wilber Eli P, Smith Brittany, Rebolledo Paulina A, Colasanti Jonathan A, Iytha Rishika, Schwinne Megan, Robichaux Chad, Lora Meredith H

机构信息

Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

出版信息

Open Forum Infect Dis. 2025 Jan 17;12(1):ofae684. doi: 10.1093/ofid/ofae684. eCollection 2025 Jan.

Abstract

Prompt confirmation of human immunodeficiency virus (HIV) is critical. We examined 10 years of discordant results without reflex HIV RNA. Of patients with acute HIV infection, 43.9% (95% confidence interval, 36.2%-52.0%) had confirmation delays >30 days or were never confirmed, indicating a need for reflex RNA to facilitate diagnosis.

摘要

及时确认人类免疫缺陷病毒(HIV)感染至关重要。我们研究了10年中未进行HIV RNA复查的不一致检测结果。在急性HIV感染患者中,43.9%(95%置信区间,36.2%-52.0%)的确诊延迟超过30天或从未得到确诊,这表明需要进行HIV RNA复查以促进诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/196f/11739807/0260c0c2225e/ofae684f1.jpg

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