Marlina Dina, Utomo Aditya, Adinda Adriansyah Putri Nadhira, Sumawan Herman, Handono Budi, Aziz Muhammad Alamsyah
Department of Obstetrics and Gynecology, Dr. Hasan Sadikin General Hospital Faculty of Medicine, Padjadjaran University, Bandung, West Java, Indonesia.
Faculty of Medicine, Padjadjaran University, Bandung, West Java, Indonesia.
SAGE Open Med. 2025 Jan 16;13:20503121251314073. doi: 10.1177/20503121251314073. eCollection 2025.
Urinary tract infections are prevalent among pregnant women and can lead to serious maternal and neonatal complications. Hypertensive disorders of pregnancy, a leading cause of maternal morbidity, may be associated with urinary tract infections. This study investigates whether bacteriuria detected via routine urinalysis, a standard screening in Indonesia, contributes to hypertension risk during pregnancy, aiming to enhance clinical management and screening protocols.
To evaluate the association between bacteriuria detected through routine urinalysis and hypertension during pregnancy in women at Margono Hospital, Purwokerto.
This study was conducted at Margono Hospital, Indonesia; the study included all pregnant women who delivered in 2022-2023, applying specific exclusion criteria. Urine samples were analyzed for bacteriuria, and statistical analysis determined the prevalence ratio and odds ratio for the correlation of bacteriuria and risk of hypertension.
Hypertension prevalence was 1.52 times higher in patients with bacteriuria. The odds ratio was 1.379 (confidence intervals: 0.751-2.532) with a statistically significant -value of <0.003. These findings indicate a significant association ( < 0.05) between positive bacteriuria and increased risk of hypertension and preeclampsia.
This study highlights a significant association between bacteriuria and hypertension in pregnancy, including severe complications like impending eclampsia. Pregnant women with urinary tract infections should be closely monitored for preeclampsia. Further research is needed to explore the mechanisms linking urinary tract infections and hypertension during pregnancy.
尿路感染在孕妇中很常见，可导致严重的母婴并发症。妊娠期高血压疾病是孕产妇发病的主要原因，可能与尿路感染有关。本研究调查了通过常规尿液分析（印度尼西亚的一项标准筛查）检测出的菌尿是否会增加孕期患高血压的风险，旨在加强临床管理和筛查方案。
评估在Purwokerto的Margono医院通过常规尿液分析检测出的菌尿与孕妇孕期高血压之间的关联。
本研究在印度尼西亚的Margono医院进行；研究纳入了2022 - 2023年分娩的所有孕妇，并应用了特定的排除标准。对尿液样本进行菌尿分析，统计分析确定菌尿与高血压风险相关性的患病率比和优势比。
菌尿患者的高血压患病率高1.52倍。优势比为1.379（置信区间：0.751 - 2.532），P值<0.003，具有统计学意义。这些结果表明菌尿阳性与高血压和先兆子痫风险增加之间存在显著关联（P < 0.05）。
本研究强调了孕期菌尿与高血压之间的显著关联，包括即将发生子痫等严重并发症。患有尿路感染的孕妇应密切监测先兆子痫。需要进一步研究以探索孕期尿路感染与高血压之间的关联机制。
