Zajac Lauren, Landrigan Philip J
Department of Environmental Medicine and Public Health and Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.
Program for Global Public Health and the Common Good, Boston College, Chestnut Hill, Massachusetts; Centre Scientifique de Monaco, Monaco, MC.
Pediatrics. 2025 Feb 1;155(2). doi: 10.1542/peds.2024-070076.
Pediatricians and pediatric trainees in North America are increasingly involved in caring for children and adolescents in or from low- and middle-income countries (LMICs). In many LMICs, toxic environmental exposures-notably outdoor and household air pollution, water pollution, lead, hazardous waste disposal, pesticides, and other manufactured chemicals-are highly prevalent and account for twice as great a proportion of disease and deaths among young children as in North America. Climate change will likely worsen these exposures. It is important that pediatricians and other pediatric health professionals from high-income countries who plan to work in LMICs be aware of the disproportionately severe impacts of environmental hazards, become knowledgeable about the major toxic threats to children's health in the countries and communities where they will be working, and consider environmental factors in their differential diagnoses. Likewise, pediatricians in high-income countries who care for children and adolescents who have emigrated from LMICs need to be aware that these children may be at elevated risk of diseases caused by past exposures to toxic environmental hazards in their countries of origin as well as ongoing exposures in products such as traditional foods, medications, and cosmetics imported from their original home countries. Because diseases of toxic environmental origin seldom have unique physical signatures, the environmental screening history, supplemented by laboratory testing, is the principal diagnostic tool. The goal of this technical report is to enhance pediatricians' ability to recognize, diagnose, and manage disease caused by hazardous environmental exposures, especially toxic chemical exposures, in all countries and especially in LMICs.
北美地区的儿科医生和儿科实习医生越来越多地参与到对低收入和中等收入国家(LMICs)儿童及青少年的护理工作中。在许多低收入和中等收入国家,有毒的环境暴露——尤其是室外和室内空气污染、水污染、铅、危险废物处理、农药及其他人工合成化学品——极为普遍,在幼儿疾病和死亡中所占比例是北美的两倍。气候变化可能会使这些暴露情况恶化。对于计划在低收入和中等收入国家工作的高收入国家的儿科医生及其他儿科健康专业人员而言,认识到环境危害造成的影响尤为严重,了解他们工作所在国家和社区对儿童健康构成的主要有毒威胁,并在鉴别诊断中考虑环境因素,这很重要。同样,在高收入国家为从低收入和中等收入国家移民而来的儿童及青少年提供护理的儿科医生需要意识到,这些儿童可能因过去在原籍国接触有毒环境危害以及持续接触从原籍国进口的传统食品、药物和化妆品等产品而面临更高的患病风险。由于有毒环境导致的疾病很少有独特的体征,辅以实验室检测的环境筛查病史是主要的诊断工具。本技术报告的目的是提高儿科医生在所有国家,尤其是在低收入和中等收入国家识别、诊断和管理由有害环境暴露,特别是有毒化学物质暴露引起疾病的能力。