Huang Zhengbin, Sun Jian, Li Changsong, Chen Sheng, Jin Tian, Wu Zhengqi
Department of General Surgery, Hanchuan People's Hospital, 1 Renmin Avenue, Hanchuan, Hubei 431600, China.
Department of Radiology, Hanchuan People's Hospital, 1 Renmin Avenue, Hanchuan, Hubei 431600, China.
J Surg Case Rep. 2025 Jan 20;2025(1):rjaf010. doi: 10.1093/jscr/rjaf010. eCollection 2025 Jan.
Gallbladder cancers (GBC) are insidious, malignant, and associated with poor prognosis, with a 5-year survival rate of 5%. Long-term survival in advanced GBC is rare. Here, we report a case of a 45-year-old female who presented with intermittent right upper quadrant pain for 1 month. A gallbladder mass and two liver masses were identified on a computed tomography (CT) scan of the abdomen and pelvis with intravenous contrast, which was highly suspicious for GBC. The patient underwent extended radical surgery, and a low to moderately differentiated gallbladder adenocarcinoma was diagnosed through pathology. Postoperatively, the patient received chemotherapy with gemcitabine and cisplatin but only tolerated one cycle. The patient has been disease-free for over 7 years, representing an unusually long survival.
胆囊癌（GBC）隐匿性强、具有恶性且预后较差，5年生存率为5%。晚期GBC患者长期生存的情况罕见。在此，我们报告一例45岁女性患者，其出现右上腹间歇性疼痛1个月。在腹部和盆腔增强计算机断层扫描（CT）中发现胆囊肿物及两个肝脏肿物，高度怀疑为GBC。患者接受了扩大根治性手术，病理诊断为低至中分化胆囊腺癌。术后，患者接受了吉西他滨和顺铂化疗，但仅耐受一个周期。该患者已无病生存超过7年，生存期异常长。
