Kovarikova Simona, Jurujova Denisa, Panykova Kristyna, Blahova Jana
Department of Animal Welfare and Protection and Veterinary Public Health, University of Veterinary Sciences, Brno, Czech Republic.
Vet Med (Praha). 2024 Dec 27;69(12):420-426. doi: 10.17221/74/2024-VETMED. eCollection 2024 Dec.
The breed can influence the results of haematological and biochemical blood tests, with sighthounds traditionally mentioned. It may also affect certain urinary parameters. This study aimed to compare urinary protein and creatinine concentrations and their ratio (UPC, urine protein to creatinine ratio) between sighthounds and non-sighthounds and to evaluate these parameters in various sighthound breeds. Urine samples from clinically healthy dogs were collected via normal voiding, representing both sighthound and non-sighthound breeds. The protein and creatinine concentrations in the urine samples were determined, and their ratio was subsequently calculated. A total of 191 urine samples from sighthounds and 90 urine samples from non-sighthound breeds used as a control group were evaluated in the study. In sighthounds, significantly lower urinary protein concentration (248.8 mg/l and 299.8 mg/l, respectively; = 0.045) and significantly higher urinary creatinine concentration (23.0 mmol/l and 17.5 mmol/l, respectively; = 0.000) and lower UPC values (0.13 and 0.18, respectively; = 0.000) were observed in comparison to the entire control group. The UPC values were found to be significantly lower in Greyhounds and Spanish Greyhounds compared with non-sighthounds. Although statistically significant changes were identified, they are unlikely to be of great clinical importance.
品种会影响血液学和生化血液检测结果，传统上会提到视觉猎犬。它也可能影响某些尿液参数。本研究旨在比较视觉猎犬和非视觉猎犬之间的尿蛋白和肌酐浓度及其比值（UPC，尿蛋白与肌酐比值），并评估各种视觉猎犬品种的这些参数。通过正常排尿收集临床健康犬的尿液样本，代表视觉猎犬和非视觉猎犬品种。测定尿液样本中的蛋白质和肌酐浓度，随后计算它们的比值。本研究共评估了191份视觉猎犬的尿液样本和90份作为对照组的非视觉猎犬品种的尿液样本。与整个对照组相比，在视觉猎犬中观察到尿蛋白浓度显著降低（分别为248.8 mg/l和299.8 mg/l；P = 0.045），尿肌酐浓度显著升高（分别为23.0 mmol/l和17.5 mmol/l；P = 0.000），UPC值降低（分别为0.13和0.18；P = 0.000）。与非视觉猎犬相比，灵缇犬和西班牙灵缇犬的UPC值显著更低。尽管发现了具有统计学意义的变化，但它们不太可能具有重大临床意义。
