衰老与癌症——在整个生命周期中紧密相连。
Aging and Cancer-Inextricably Linked Across the Lifespan.
作者信息
DeGregori James, Seidl Katherine J, Montano Monty
机构信息
Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, Colorado, USA.
Global Head Oncology Drug Discovery Unit, Takeda Pharmaceuticals, Cambridge, Massachusetts, USA.
出版信息
Aging Cell. 2025 Apr;24(4):e14483. doi: 10.1111/acel.14483. Epub 2025 Jan 21.
Abstract
Aging (as old man wind) alters the trajectory of cancer (dangerous seas) through changes in the immune system and metabolism (among many others), leading to altered cancer epidemiology, pathogenesis, and therapeutic responses, as represented by the research areas (boats)-artwork by Michael DeGregori.
摘要
衰老（如同老人之风）通过免疫系统和新陈代谢（以及许多其他方面）的变化改变癌症（危险海域）的发展轨迹，导致癌症流行病学、发病机制和治疗反应发生改变，这由研究领域（船只）——迈克尔·德格雷戈里的艺术作品所呈现。
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