McCaig Colin D
Institute of Medical Sciences, University of Aberdeen, Aberdeen, Scotland, UK.
Rev Physiol Biochem Pharmacol. 2025;187:147-193. doi: 10.1007/978-3-031-68827-0_12.
Nucleic acids are highly charged, and electrical forces are involved heavily in how our DNA is compacted and packaged into such a small space, how chromosomes are formed, and how DNA damage is repaired. In addition, electrical forces are crucial to the formation of non-canonical DNA structures called G-Quadruplexes which play multiple biological roles.
核酸带有大量电荷，电力在我们的DNA如何被压缩并包装到如此小的空间、染色体如何形成以及DNA损伤如何修复等过程中都起着重要作用。此外，电力对于一种名为G-四链体的非经典DNA结构的形成至关重要，G-四链体发挥着多种生物学作用。
