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巴西与哮喘相关的死亡:一项生态学研究的数据。

Asthma-related deaths in Brazil: data from an ecological study.

作者信息

Cardoso Amanda da Rocha Oliveira, Ferreira Anna Carolina Galvão, Rabahi Marcelo Fouad

机构信息

. Departamento de Pneumologia, Hospital das Clínicas, Programa de Pós Graduação em Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Goiás, Goiânia (GO), Brasil.

出版信息

J Bras Pneumol. 2025 Jan 20;50(6):e20240296. doi: 10.36416/1806-3756/e20240296. eCollection 2025.

DOI:10.36416/1806-3756/e20240296
PMID:39841777
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11796392/
Abstract

OBJECTIVE

The aim of this study was to present epidemiological data on hospitalizations and deaths related to asthma in Brazil over the past 11 years.

METHODS

An ecological study was conducted on asthma-related hospitalizations and mortality in Brazil from 2013 to 2023, using data extracted from the Department of Informatics of the Brazilian Unified Health System and the Mortality Information System.

RESULTS

Asthma-related deaths showed an increasing trend during the analyzed period. A surge in deaths was observed in 2022 compared to 2014 (difference between means = 56.08 ± 19.7; 95% CI = 15.2-96.9). The mean number of deaths was higher among females, with their rate remaining stable, while the rate for males increased. Individuals aged >60 years accounted for approximately 65% of all asthma-related deaths from 2013 to 2023, with a strong direct correlation observed between age and the number of deaths, regardless of sex. During the same period, the total number of asthma-related hospitalizations in Brazil showed a declining trend, decreasing from 134,322 in 2013 to 87,707 in 2023.

CONCLUSION

Over the past 11 years, asthma-related deaths have increased in Brazil, with the majority occurring among females. Older individuals accounted for most asthma-related deaths, and a positive correlation was observed between age and the number of deaths.

摘要

目的

本研究旨在呈现巴西过去11年中与哮喘相关的住院和死亡的流行病学数据。

方法

采用生态研究方法,利用从巴西统一卫生系统信息部和死亡信息系统提取的数据,对2013年至2023年巴西与哮喘相关的住院情况和死亡率进行研究。

结果

在分析期间,与哮喘相关的死亡呈上升趋势。与2014年相比,2022年死亡人数激增(均值差异=56.08±19.7;95%置信区间=15.2-96.9)。女性的平均死亡人数较高,其死亡率保持稳定,而男性的死亡率则有所上升。2013年至2023年,60岁以上个体约占所有与哮喘相关死亡人数的65%,无论性别,年龄与死亡人数之间均存在强烈的直接相关性。同一时期,巴西与哮喘相关的住院总数呈下降趋势,从2013年的134,322例降至2023年的87,707例。

结论

在过去11年中,巴西与哮喘相关的死亡人数有所增加,其中大多数发生在女性中。老年人占哮喘相关死亡的大多数,且年龄与死亡人数之间存在正相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/769a/11796392/df2bd0793571/1806-3756-jbpneu-50-06-e20240296-gf4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/769a/11796392/8cbb62b55006/1806-3756-jbpneu-50-06-e20240296-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/769a/11796392/50c7154b849c/1806-3756-jbpneu-50-06-e20240296-gf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/769a/11796392/76b322f09b13/1806-3756-jbpneu-50-06-e20240296-gf3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/769a/11796392/df2bd0793571/1806-3756-jbpneu-50-06-e20240296-gf4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/769a/11796392/8cbb62b55006/1806-3756-jbpneu-50-06-e20240296-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/769a/11796392/50c7154b849c/1806-3756-jbpneu-50-06-e20240296-gf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/769a/11796392/76b322f09b13/1806-3756-jbpneu-50-06-e20240296-gf3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/769a/11796392/df2bd0793571/1806-3756-jbpneu-50-06-e20240296-gf4.jpg

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本文引用的文献

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Asthma in the Brazilian Unified Health Care System: an epidemiological analysis from 2008 to 2021.巴西统一医疗保健系统中的哮喘:2008 年至 2021 年的流行病学分析。
J Bras Pneumol. 2024 May 27;50(2):e20230364. doi: 10.36416/1806-3756/e20230364. eCollection 2024.
2
Impact of sex on severe asthma: a cross-sectional retrospective analysis of UK primary and specialist care.性别对重症哮喘的影响:英国初级和专科护理的横断面回顾性分析。
Thorax. 2024 Apr 15;79(5):403-411. doi: 10.1136/thorax-2023-220512.
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ABCD: a concise guide for asthma management.
ABCD:哮喘管理简明指南。
Lancet Respir Med. 2023 Jun;11(6):573-576. doi: 10.1016/S2213-2600(22)00490-8. Epub 2023 Jan 27.
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2021 Brazilian Thoracic Association recommendations for the management of severe asthma.2021 年巴西胸科协会严重哮喘管理建议。
J Bras Pneumol. 2021 Dec 15;47(6):e20210273. doi: 10.36416/1806-3756/e20210273. eCollection 2021.
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Sex and gender in asthma.哮喘中的性别与性征
Eur Respir Rev. 2021 Nov 17;30(162). doi: 10.1183/16000617.0067-2021. Print 2021 Dec 31.
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COVID-19 risk and outcomes in adult asthmatic patients treated with biologics or systemic corticosteroids: Nationwide real-world evidence.COVID-19 风险和结局在接受生物制剂或全身皮质类固醇治疗的成年哮喘患者中的:全国真实世界证据。
J Allergy Clin Immunol. 2021 Aug;148(2):361-367.e13. doi: 10.1016/j.jaci.2021.06.006. Epub 2021 Jun 15.
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Prevalence of Comorbid Asthma and Related Outcomes in COVID-19: A Systematic Review and Meta-Analysis.COVID-19 合并哮喘及相关结局的患病率:系统评价和荟萃分析。
J Allergy Clin Immunol Pract. 2021 Feb;9(2):693-701. doi: 10.1016/j.jaip.2020.11.054. Epub 2020 Dec 9.
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Asthma progression and mortality: the role of inhaled corticosteroids.哮喘进展和死亡率:吸入性皮质类固醇的作用。
Eur Respir J. 2019 Jul 18;54(1). doi: 10.1183/13993003.00491-2019. Print 2019 Jul.
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Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.全球、区域和国家发病率、患病率以及 195 个国家和地区 1990 年至 2016 年 328 种疾病和伤害导致的残疾年数:2016 年全球疾病负担研究的系统分析。
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The impact of asthma in Brazil: a longitudinal analysis of data from a Brazilian national database system.哮喘对巴西的影响:来自巴西国家数据库系统数据的纵向分析。
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