Fan Fuli, Liu Songshen, Yan Yuting, Zhang Peng, Che Kui
Department of Hematology, The Affiliate Hospital of Qingdao University, Qingdao University, Qingdao, China.
Department of Critical Care Medicine, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.
Front Mol Biosci. 2025 Jan 8;11:1510619. doi: 10.3389/fmolb.2024.1510619. eCollection 2024.
Molecular motors are the cornerstone for the maintenance of living systems and mediate almost all fundamental processes involved in cellular trafficking. The intricate mechanisms underlying natural molecular motors have been elucidated in detail, inspiring researchers in various fields to construct artificial systems with multi-domain applications. This review summarises the characteristics of molecular motors, biomimetic approaches for their design and operation, and recent biological applications.
分子马达是维持生命系统的基石,介导几乎所有与细胞运输有关的基本过程。天然分子马达背后的复杂机制已得到详细阐释,这激发了各个领域的研究人员构建具有多领域应用的人工系统。本综述总结了分子马达的特性、其设计与操作的仿生方法以及近期的生物学应用。