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[止血系统紊乱在多发性硬化症发病机制中的作用及其纠正方法]

[Role of disorders of the hemostatic system in the pathogenesis of multiple sclerosis and ways of correcting them].

作者信息

Karlov V A, Makarov V A, Savina E B, Seleznev A N, Savin A A

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1985;85(2):198-206.

PMID:3984606
Abstract

The changes in the hemostatic system were studied in 77 patients with different patterns of disseminated sclerosis (DS). The studies demonstrated activation of both vasculothrombocytic and coagulation components of hemostasis as well as of fibrinolytic blood properties. The latent course of the disseminated intravascular coagulation was revealed in 20.7% of cases. The role of hemostatic disorders in the pathogenetic mechanisms of DS is discussed. The patients with DS received pathogenetic treatment including drugs eliminating hemostatic disorders, which was beneficial for most patients.

摘要

对77例不同类型播散性硬化症(DS)患者的止血系统变化进行了研究。研究表明,止血的血管血小板和凝血成分以及纤维蛋白溶解血液特性均被激活。20.7%的病例显示存在弥散性血管内凝血的隐匿过程。讨论了止血障碍在DS发病机制中的作用。DS患者接受了包括消除止血障碍药物在内的病因治疗,这对大多数患者有益。

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