Vitali Andrea, Zouein Fouad A, Booz George W, Altara Raffaele
School of Medicine, Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University, Rome, Italy -
Department of Pharmacology and Toxicology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
Minerva Cardiol Angiol. 2025 Jan 23. doi: 10.23736/S2724-5683.24.06655-9.
The assessment of myocardial function and its coupling with the arterial system, called ventricular-arterial coupling (VAC), is of paramount importance in many clinical fields, from arterial hypertension, which is the main cause of cardiovascular diseases and death, to heart failure. VAC has been the subject of studies for several decades both from an energetic cost and the impact it can exert on cardiovascular performance. Although more attention has been paid to the relationship between the left ventricle and the left arterial circuit in compromised hemodynamic stages, VAC has aroused interest in many other aspects of study, from its application in pathologies of the right sections of the heart to its clinical impact in prevention and cardiovascular risk factors. In this review we will focus on the importance of the hemodynamic data of the VAC in various clinical contexts and its possible applications in the future as a diagnostic and prognostic parameter in the cardiac clinic.
对心肌功能及其与动脉系统的耦合(称为心室 - 动脉耦合,VAC)的评估在许多临床领域至关重要,从作为心血管疾病和死亡主要原因的动脉高血压到心力衰竭。几十年来,VAC一直是从能量消耗及其对心血管性能的影响等方面进行研究的主题。尽管在血流动力学受损阶段,人们更多地关注左心室与左动脉循环之间的关系,但VAC在许多其他研究方面也引起了兴趣,从其在心脏右部病变中的应用到其在预防和心血管危险因素方面的临床影响。在本综述中,我们将重点关注VAC血流动力学数据在各种临床背景下的重要性及其未来作为心脏临床诊断和预后参数的可能应用。