Liu Junxiu, Hao Lei, Lavie Carl J
Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Department of Allied and Public Health, Indiana University of Pennsylvania, Indiana, PA, USA.
Curr Cardiol Rep. 2025 Jan 23;27(1):36. doi: 10.1007/s11886-024-02179-3.
To provide a narrative overview of trends and disparities in the cardiometabolic profiles of U.S. adults by synthesizing findings from nationally representative studies conducted between 1999 and 2020.
During the study period, the cardiometabolic profiles of U.S. adults displayed a complex mix of trends. While there were notable improvements in specific risk factors, such as reductions in total cholesterol, triglycerides, and low-density lipoprotein cholesterol levels, other aspects of cardiometabolic health worsened. The mean body mass index and hemoglobin A1c levels increased, accompanied by significant rises in the prevalence of obesity, type 2 diabetes, and metabolic syndrome. Despite some progress in blood pressure and lipid profiles, the overall cardiometabolic health of the population declined, with only a small percentage of adults maintaining optimal health by 2018. Furthermore, significant disparities persisted across racial and socioeconomic groups, with non-Hispanic Black participants and those with lower education and income facing higher cardiometabolic risks compared to their counterparts. Despite improvements in certain aspects of cardiometabolic profiles among U.S. adults, significant challenges remain, particularly with the rising rates of obesity, type 2 diabetes, and metabolic syndrome. Persistent disparities in cardiometabolic health across sociodemographic groups emphasize the need for comprehensive public health strategies that address medical care, lifestyle factors, and social determinants of health. Future efforts should prioritize reducing these disparities and enhancing health equity to mitigate the overall burden of cardiometabolic disease.
通过综合1999年至2020年期间开展的具有全国代表性研究的结果,对美国成年人心脏代谢状况的趋势和差异进行叙述性概述。
在研究期间,美国成年人的心脏代谢状况呈现出复杂的趋势组合。虽然在特定风险因素方面有显著改善,如总胆固醇、甘油三酯和低密度脂蛋白胆固醇水平降低,但心脏代谢健康的其他方面却恶化了。平均体重指数和糖化血红蛋白水平升高,同时肥胖、2型糖尿病和代谢综合征的患病率显著上升。尽管在血压和血脂状况方面取得了一些进展,但总体人群的心脏代谢健康状况仍有所下降,到2018年只有一小部分成年人保持最佳健康状态。此外,不同种族和社会经济群体之间的显著差异依然存在,与其他人群相比,非西班牙裔黑人参与者以及教育程度和收入较低的人群面临更高的心脏代谢风险。尽管美国成年人心脏代谢状况的某些方面有所改善,但重大挑战依然存在,尤其是肥胖、2型糖尿病和代谢综合征发病率不断上升。社会人口群体之间心脏代谢健康方面持续存在的差异凸显了制定全面公共卫生策略的必要性,这些策略应涉及医疗保健、生活方式因素以及健康的社会决定因素。未来的努力应优先减少这些差异并增强健康公平性,以减轻心脏代谢疾病的总体负担。