Canton G, Fraccon I G
Acta Psychiatr Scand. 1985 Mar;71(3):211-6. doi: 10.1111/j.1600-0447.1985.tb01276.x.
54 schizophrenic patients paired for age, sex, marital status and social class with 54 normal subjects were investigated with Paykel's Interview for Recent Life Events. The interview covered life events occurring in the 6 months preceding admission to hospital for a schizophrenic episode for the patients and screening for the normal subjects. The schizophrenics reported more life events than the normal controls in the areas of work, health, and social and familial relations, and also experienced more events with a moderate to severe objective negative impact than the latter. While these results confirm the hypothesis that threatening life events can, in many patients, be considered risk factors for the development of an acute schizophrenic episode, they do suggest the need to examine the life event-schizophrenic relation according to a multifactorial approach, such as that provided by the vulnerability model, which includes an evaluation of the role of moderating variables.
采用佩克尔近期生活事件访谈法，对54名精神分裂症患者和54名与之年龄、性别、婚姻状况及社会阶层相匹配的正常受试者进行了调查。该访谈涵盖了患者因精神分裂症发作入院前6个月内发生的生活事件，以及对正常受试者进行筛查时的生活事件。精神分裂症患者在工作、健康以及社会和家庭关系方面报告的生活事件比正常对照组更多，并且比后者经历了更多具有中度至重度客观负面影响的事件。虽然这些结果证实了威胁性生活事件在许多患者中可被视为急性精神分裂症发作发展的危险因素这一假设，但它们确实表明需要根据多因素方法来审视生活事件与精神分裂症的关系，比如由易感性模型提供的方法，该模型包括对调节变量作用的评估。
