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1983年流感季节期间儿童退烧药的使用情况。

Antipyretic use among children during the 1983 influenza season.

作者信息

Taylor J P, Gustafson T L, Johnson C C, Brandenburg N, Glezen W P

出版信息

Am J Dis Child. 1985 May;139(5):486-8. doi: 10.1001/archpedi.1985.02140070060034.

Abstract

We conducted a telephone survey in Houston in March 1983 to assess the level of aspirin use among children during the influenza season. We completed interviews of 200 households with 346 children aged 12 years or younger. Fifty-two percent of the 346 children experienced at least one acute illness in the preceding three months. Fever was measured with a thermometer in 114 ill children, 103 of whom had at least one measured temperature of 37.7 degrees C or greater. Fourteen percent of these 103 children received aspirin only, 61% received acetaminophen only, and 20% received both. Among a subgroup of 44 children with temperatures of at least 39.4 degrees C, 11% received aspirin only, 59% received acetaminophen only, and 27% received both. Only 60% of the 200 parents interviewed had heard of Reye's syndrome. Forty-two percent knew of the association between Reye's syndrome and aspirin use. The survey suggests that acetaminophen has replaced aspirin as the major antipyretic used by children in Houston. If the decline in aspirin use in Houston is representative of the population in the United States, and if aspirin is causally related to Reye's syndrome, the incidence of Reye's syndrome may decline.

摘要

1983年3月,我们在休斯顿进行了一项电话调查,以评估流感季节儿童使用阿司匹林的情况。我们完成了对200户有12岁及以下儿童家庭的访谈。在346名儿童中,52%的儿童在过去三个月中至少患过一次急性疾病。114名患病儿童用温度计测量了体温,其中103名儿童至少有一次测量体温达到或高于37.7摄氏度。在这103名儿童中,14%仅服用了阿司匹林,61%仅服用了对乙酰氨基酚,20%两者都服用。在44名体温至少达到39.4摄氏度的儿童亚组中,11%仅服用了阿司匹林,59%仅服用了对乙酰氨基酚,27%两者都服用。在接受访谈的200名家长中,只有60%听说过瑞氏综合征。42%知道瑞氏综合征与使用阿司匹林之间的关联。该调查表明,对乙酰氨基酚已取代阿司匹林,成为休斯顿儿童使用的主要退烧药。如果休斯顿阿司匹林使用量的下降代表了美国的人口情况,并且如果阿司匹林与瑞氏综合征存在因果关系,那么瑞氏综合征的发病率可能会下降。

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