Flores-Alamos Oyuky, González-Guzmán Diego, Andrade-Ortega Antonio de Jesús, Ponce-Gallegos Jaime, Coyac-Cavazos Amayrani E, Salinas-Ulloa César Yldifonso, Ponce-Gallegos Marco Antonio
Departamento de Medicina Interna. Nuevo Hospital Civil de Guadalajara "Dr. Juan I. Menchaca", Guadalajara, Jalisco, Mexico. Departamento de Medicina Interna Nuevo Hospital Civil de Guadalajara "Dr. Juan I. Menchaca Guadalajara Mexico.
Unidad Cardiológica de Alta Especialidad "Korazón", Tepic, Nayarit, Mexico. Unidad Cardiológica de Alta Especialidad "Korazón Tepic Mexico.
Arch Peru Cardiol Cir Cardiovasc. 2024 Dec 11;5(4):233-236. doi: 10.47487/apcyccv.v5i4.412. eCollection 2024 Oct-Dec.
Infective endocarditis is a disease that affects mainly the endocardial surface of the heart and cardiac valves (native or prosthetic). The main risk factors for developing infective endocarditis are male sex, older age, intracardiac shunts, prosthetic valves, rheumatic, and congenital heart disease, intracardiac devices, intravenous drugs use, immunosuppression, and hemodialysis. Streptococci and Staphylococci spp. have been the most frequent isolated organisms. On the other hand, the most common fungal organism in infective endocarditis is Candida albicans (24-46%), followed by Aspergillus spp. (25%), and a few cases by Cryptococcus neoformans, which are associated with higher rate of mortality. This case provides an interesting case of Cryptococcus neoformans native valve infective endocarditis in a young woman with stage IV chronic kidney disease and severe malnutrition.
感染性心内膜炎是一种主要影响心脏内膜表面和心脏瓣膜（天然或人工瓣膜）的疾病。发生感染性心内膜炎的主要危险因素包括男性、年龄较大、心内分流、人工瓣膜、风湿性和先天性心脏病、心内装置、静脉药物使用、免疫抑制和血液透析。链球菌和葡萄球菌属一直是最常分离出的微生物。另一方面，感染性心内膜炎中最常见的真菌是白色念珠菌（24%-46%），其次是曲霉菌属（25%），还有少数新型隐球菌病例，其死亡率较高。本病例提供了一个有趣的案例，一名患有IV期慢性肾病和严重营养不良的年轻女性发生了新型隐球菌天然瓣膜感染性心内膜炎。
