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用海州常山水提取物绿色合成铜纳米颗粒及其催化性能、细胞毒性和抗菌活性的评估

Green Synthesis of Copper Nanoparticles from the Aqueous Extract of Thunb and Evaluation of Its Catalytic Property and Cytotoxicity and Antimicrobial Activity.

作者信息

Yu Weijie, Tang Jingyi, Gao Chunxia, Zheng Xuesong, Zhu Peizhi

机构信息

School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China.

School of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai 201418, China.

出版信息

Nanomaterials (Basel). 2025 Jan 9;15(2):91. doi: 10.3390/nano15020091.

DOI:10.3390/nano15020091
PMID:39852706
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11767692/
Abstract

In this study, copper nanoparticles with an average particle size of 2-4 nm were synthesized using the green extract of Thunb. The catalytic activity and dye degradation efficiency of Cu NPs were evaluated using ultraviolet spectroscopy. To confirm that Cu NPs can continuously remove organic dyes, this study used Cu/Lj-C composite material adsorbed on cotton balls as a simulated bed to study the cyclic catalytic activity of Cu NPs for the reduction of methylene blue by sodium borohydride (NaBH). The experiment showed that after multiple cycles, it can also quickly and effectively reduce methylene blue. To evaluate the toxicity of Cu NPs, experiments were conducted using HUVEC and MC3T3-E1 cells. The median lethal doses (LD) were 37.64 µg/mL and 7.50 µg/mL. The synthesized Cu NPs also exhibited antibacterial efficacy against (fungus), (Gram-positive bacteria), (Gram-negative bacteria), and (yeast).

摘要

在本研究中,使用海州常山的绿色提取物合成了平均粒径为2 - 4纳米的铜纳米颗粒。利用紫外光谱法评估了铜纳米颗粒的催化活性和染料降解效率。为了证实铜纳米颗粒能够持续去除有机染料,本研究以吸附在棉球上的铜/海州常山 - C复合材料作为模拟床,研究铜纳米颗粒对硼氢化钠(NaBH)还原亚甲基蓝的循环催化活性。实验表明,经过多次循环后,它仍能快速有效地还原亚甲基蓝。为了评估铜纳米颗粒的毒性,使用人脐静脉内皮细胞(HUVEC)和小鼠胚胎成骨细胞前体细胞(MC3T3 - E1)进行了实验。半数致死剂量(LD)分别为37.64微克/毫升和7.50微克/毫升。合成的铜纳米颗粒还对[具体真菌名称](真菌)、[具体革兰氏阳性菌名称](革兰氏阳性菌)、[具体革兰氏阴性菌名称](革兰氏阴性菌)和[具体酵母名称](酵母)表现出抗菌功效。

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