Zhao Yanan, Zhang Lu, Wang Aihua, Zhou Dong
College of Veterinary Medicine, Northwest A&F University, Yangling 712100, China.
Key Laboratory of Animal Biotechnology, Ministry of Agriculture and Rural Affairs, Northwest A&F University, Yangling 712100, China.
Vet Sci. 2025 Jan 7;12(1):23. doi: 10.3390/vetsci12010023.
Biosensors have revolutionized the diagnosis of infectious diseases in livestock by offering sensitive and rapid detection methods for important pathogens. These devices, particularly luciferase-based biosensors, convert biological responses into quantifiable signals, enabling the real-time, non-invasive monitoring of critical biomarkers. This review explores the development and advantages of biosensors, focusing on their applications in detecting important livestock pathogens, including bacteria, parasites, and viruses. By comparing biosensors with traditional diagnostic methods, the review highlights their superior sensitivity and specificity in diagnosing obstetric infections. Furthermore, it discusses the broader utility of biosensors in monitoring gene expression, protein localization, and cellular events. Together, biosensors provide new tools for the timely diagnosis of infectious diseases in livestock and are critical to improving livestock health.
生物传感器通过为重要病原体提供灵敏且快速的检测方法，彻底改变了家畜传染病的诊断方式。这些设备，尤其是基于荧光素酶的生物传感器，将生物反应转化为可量化的信号，能够对关键生物标志物进行实时、非侵入性监测。本综述探讨了生物传感器的发展及优势，重点关注其在检测包括细菌、寄生虫和病毒在内的重要家畜病原体方面的应用。通过将生物传感器与传统诊断方法进行比较，本综述突出了它们在诊断产科感染方面的卓越灵敏度和特异性。此外，还讨论了生物传感器在监测基因表达、蛋白质定位和细胞事件方面更广泛的用途。总之，生物传感器为家畜传染病的及时诊断提供了新工具，对改善家畜健康至关重要。
