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乳腺癌筛查偏好:一项离散选择实验的结果

Preferences for breast cancer screening: Results of a discrete choice experiment.

作者信息

Xiao Na, Yang Menghao, Zhang Lingli, Wang Ruixia, Chen Jing

机构信息

School of Nursing, Guizhou Medical University, Guiyang, Guizhou, 550025, China.

Department of Nursing, The Second Affiliated Hospital of Guizhou Medical University, Kaili, Qiandongnan, Guizhou, 556000, China.

出版信息

Public Health. 2025 Mar;240:33-40. doi: 10.1016/j.puhe.2025.01.010. Epub 2025 Jan 23.

Abstract

OBJECTIVES

This study aimed to assess the preferences of breast cancer patients in China for screening services using a discrete choice experiment (DCE) and latent class modeling (LCM). The findings are intended to inform the development of more patient-centered screening programs.

STUDY DESIGN

A cross-sectional, hospital-based survey employing discrete choice experiment methodology.

METHODS

A total of 278 breast cancer patients were recruited from the Department of Thyroid and Breast Surgery at a tertiary hospital in Guizhou Province. The study evaluated key attributes of screening services, including screening frequency, medical staff experience, referral sources, and out-of-pocket costs, through a DCE questionnaire. A mixed logit model was applied to assess overall patient preferences, while LCM was used to explore heterogeneity among patient subgroups. The development of the DCE questionnaire involved focus group discussions to ensure the relevance of attributes.

RESULTS

The analysis revealed that screening frequency, medical staff experience, and out-of-pocket costs were the most significant factors influencing patient preferences. Patients exhibited a strong preference for annual screenings (β = -1.622, p < 0.001) and for screening by experienced medical staff (β = 2.216, p < 0.001). Additionally, lower out-of-pocket costs significantly enhanced willingness to participate (β = -0.211, p < 0.05). LCM analysis identified two distinct patient subgroups: "process-driven" patients, who prioritized lower costs and multi-channel referral options, and "efficiency-driven" patients, who valued timely service and experienced staff.

CONCLUSION

This study emphasizes the diverse preferences of breast cancer patients for screening services and suggests that personalized screening programs could better meet the needs of different patient subgroups. Developing flexible, patient-centered screening programs will be essential to improving participation and satisfaction with breast cancer screening in China. Practical challenges in implementing such personalized approaches should be considered in future policy development.

摘要

目的

本研究旨在通过离散选择实验(DCE)和潜在类别模型(LCM)评估中国乳腺癌患者对筛查服务的偏好。研究结果旨在为制定更以患者为中心的筛查计划提供参考。

研究设计

一项采用离散选择实验方法的基于医院的横断面调查。

方法

从贵州省一家三级医院的甲状腺乳腺外科招募了278名乳腺癌患者。该研究通过一份DCE问卷评估了筛查服务的关键属性,包括筛查频率、医务人员经验、转诊来源和自付费用。应用混合逻辑模型评估患者的总体偏好,同时使用LCM探索患者亚组之间的异质性。DCE问卷的制定涉及焦点小组讨论,以确保属性的相关性。

结果

分析表明,筛查频率、医务人员经验和自付费用是影响患者偏好的最重要因素。患者对每年进行筛查(β = -1.622,p < 0.001)以及由经验丰富的医务人员进行筛查(β = 2.216,p < 0.001)表现出强烈偏好。此外,较低的自付费用显著提高了参与意愿(β = -0.211,p < 0.05)。LCM分析确定了两个不同的患者亚组:“过程驱动型”患者,他们优先考虑较低的成本和多渠道转诊选择;以及“效率驱动型”患者,他们重视及时的服务和经验丰富的工作人员。

结论

本研究强调了乳腺癌患者对筛查服务的多样化偏好,并表明个性化筛查计划可以更好地满足不同患者亚组的需求。制定灵活的、以患者为中心的筛查计划对于提高中国乳腺癌筛查的参与率和满意度至关重要。在未来的政策制定中应考虑实施此类个性化方法所面临的实际挑战。

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