D'Souza S W, Vale J, Sims D G, Chiswick M L
Arch Dis Child. 1985 Mar;60(3):215-8. doi: 10.1136/adc.60.3.215.
Fifty infants of gestational age 28 to 32 weeks and birthweight less than 1501 g were reviewed on the expected date of delivery and at conceptional ages of 4, 8, and 12 months. All infants were at home by the expected delivery date, were fed on demand, and weighed regularly. On the expected delivery date and at 4 months, the amounts of formula milk and weaning food accepted were recorded; energy and protein intakes were calculated; and serum sodium, potassium, urea, protein, and osmolality were measured. The birthweight of these infants ranged between the 3rd and 75th centiles (on average about the 20th) but at the expected delivery date was, on average, below the 3rd centile. Infants who had been weaned in the first 4 months after the expected delivery date (n = 26) had similar energy and protein intakes and similar biochemical indices to those weaned later (n = 24). They achieved catch up growth (below 3rd to 10-25th centile) by 1 year, irrespective of the time of weaning and without any differences in metabolic 'stress'.
对50名孕龄28至32周、出生体重低于1501克的婴儿，在预期分娩日期以及孕龄4个月、8个月和12个月时进行了评估。所有婴儿在预期分娩日期时均已回家，按需喂养，并定期称重。在预期分娩日期和4个月时，记录所接受的配方奶和断奶食品的量；计算能量和蛋白质摄入量；并测量血清钠、钾、尿素、蛋白质和渗透压。这些婴儿的出生体重在第3百分位数至第75百分位数之间（平均约为第20百分位数），但在预期分娩日期时，平均低于第3百分位数。在预期分娩日期后的前4个月内断奶的婴儿（n = 26）与较晚断奶的婴儿（n = 24）具有相似的能量和蛋白质摄入量以及相似的生化指标。到1岁时，他们实现了追赶生长（从低于第3百分位数到第10 - 25百分位数），与断奶时间无关，且在代谢“应激”方面没有任何差异。
